2022 - 2012

2022

Capsoni S, Arisi I, Malerba F, D’Onofrio M, Cattaneo A, Cherubini E. Targeting the Cation-Chloride Co-Transporter NKCC1 to Re-Establish GABAergic Inhibition and an Appropriate Excitatory/Inhibitory Balance in Selective Neuronal Circuits: A Novel Approach for the Treatment of Alzheimer’s Disease. Brain Sci. 2022 Jun 15;12(6):783. doi:10.3390/brainsci12060783.

Basilico B, Ferrucci L , Ratano P, Golia MT, Grimaldi A, Rosito M , Ferretti M, Reverte I, Sanchini C, Marrone MC, Giubettini M, De Turris V, Salerno D, Garofalo S, St-Pierre M, Carrier M, Renzi M, Pagani F, Modi B , Raspa M, Scavizzi F, Gross CT, Marinelli S, Tremblay ME, Caprioli D, Maggi L, Limatola C, Di Angelantonio S, Ragozzino D. Microglia control glutamatergic synapses in the adult mouse hippocampus. GLIA Jan;70(1):173-195.

Barbato G, Nisticò R, Triaca V. Exploiting Focused Ultrasound to Aid Intranasal Drug Delivery for Brain Therapy. Front Pharmacol. 2022 Apr 14;13:786475.

Ben-Ari Y, Cherubini E (2022). The GABA Polarity Shift and Bumetanide Treatment: Making Sense Requires Unbiased and Undogmatic Analysis. Cells. 2022 Jan 24;11(3):396. doi: 10.3390/cells11030396.

Capsoni S, Cattaneo A. Getting Into the Brain: The Intranasal Approach to Enhance the Delivery of Nerve Growth Factor and Its Painless Derivative in Alzheimer’s Disease and Down Syndrome. Front Neurosci. 2022 Mar 9;16:773347. doi: 10.3389/fnins.2022.773347. PMID: 35360160; PMCID: PMC8961408.

Cattaneo A, Mainardi M. Editorial: From Whole-Cell to Single Synapse Engrams – Breaking the Code for Memory Formation, Storage and Recall. Front Mol Neurosci. 2022 Mar 1;15:845516. doi: 10.3389/fnmol.2022.845516. PMID: 35310882; PMCID: PMC8926606. 

Cherubini E, Di Cristo G, Avoli M (2022). Dysregulation of GABAergic Signaling in Neurodevelomental Disorders: Targeting Cation-Chloride Co-transporters to Re-establish a Proper E/I Balance. Front Cell Neurosci. 2022 Jan 5;15:813441. doi: 10.3389/fncel.2021.813441.

Gilodi M, Lisi S, F Dudás E, Fantini M, Puglisi R, Louka A, Marcatili P, Cattaneo A, Pastore A. Selection and Modelling of a New Single-Domain Intrabody Against TDP-43. Front Mol Biosci. 2022 Feb 14;8:773234. doi: 10.3389/fmolb.2021.773234. PMID: 35237655; PMCID: PMC8884700.

Malerba F. Why Are We Scientists? Drawing Inspiration From Rita Levi-Montalcini.

Front Cell Neurosci. 2022 Jan 21;15:741984. doi: 10.3389/fncel.2021.741984. eCollection 2021. Review.

Menghini R, Hoyles L, Cardellini M, Casagrande V, Marino A, Gentileschi P, Davato F, Mavilio M, Arisi I, Mauriello A, Montanaro M, Scimeca M, Barton RH, Rappa F, Cappello F, Vinciguerra M, Moreno-Navarrete JM, Ricart W, Porzio O, Fernández-Real JM, Burcelin R, Dumas ME, Federici M. ITCH E3 ubiquitin ligase downregulation compromises hepatic degradation of branched-chain amino acids. Mol Metab. 2022 May;59:101454. doi: 10.1016/j.molmet.2022.101454. Epub 2022 Feb 9.

Micallef B, Nisticò R, Sarac SB, Bjerrum OW, Butler D, Sammut Bartolo N, Serracino-Inglott A, Borg JJ. The changing landscape of treatment options in childhood acute lymphoblastic leukaemia. Drug Discov Today. 2022 Jan 7:S1359-6446(22)00002-2. doi: 10.1016/j.drudis.2022.01.002. PMID: 35007767

Musardo S, Therin S, Pelucchi S, D’Andrea L, Stringhi R, Ribeiro A, Manca A, Balducci C, Pagano J, Sala C, Verpelli C, Grieco V, Edefonti V, Forloni G, Gardoni F, Meli G, Di Marino D, Di Luca M, Marcello E. The development of ADAM10 endocytosis inhibitors for the treatment of Alzheimer’s disease. Mol Ther. 2022 Apr 4:S1525-0016(22)00227-1. doi: 10.1016/j.ymthe.2022.03.024.

 

2021

Brandi R, Fabiano M, Giorgi C, Arisi I, La Regina F, Malerba F, Turturro S, Storti AE, Ricevuti F, Amadio S, Volontè C, Capsoni S, Scardigli R, D’Onofrio M, Cattaneo A. Nerve Growth Factor Neutralization Promotes Oligodendrogenesis by Increasing miR-219a-5p Levels. Cells. 2021 Feb 16;10(2):405. doi: 10.3390/cells10020405.

Braschi C, Capsoni S, Narducci R, Poli A, Sansevero G, Brandi R, Maffei L, Cattaneo A, Berardi N. Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis. Aging Clin Exp Res. 2021 May;33(5):1223-1238. doi: 10.1007/s40520-020-01646-5. Epub 2020 Jul 16. PMID: 32676979; PMCID: PMC8081712.

Canevelli M & Arisi I & Bacigalupo I & Arighi A & Galimberti D & Vanacore N & D’Onofrio M & Cesari M & Bruno G. Biomarkers and phenotypic expression in Alzheimer’s disease: exploring the contribution of frailty in the Alzheimer’s Disease Neuroimaging Initiative. GeroScience (2021) 43:1039–1051. https://doi.org/10.1007/s11357-020-00293-y.

Delaby C, Teunissen CE, […], Arisi I, D’Onofrio M, […], Zetterberg H and Lehmann S, “Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer’s disease: an international overview”, Alz & Dementia, 2021, Dec 22. doi: 10.1002/alz.12545.

Gatti G, Vilardo L, Musa C, Di Pietro C, Bonaventura F, Scavizzi F, Torcinaro A, Bucci B, Saporito R, Arisi I, De Santa F, Raspa M, Guglielmi L, D’Agnano I. Role of Lamin A/C as Candidate Biomarker of Aggressiveness and Tumorigenicity in Glioblastoma Multiforme. Biomedicines. 2021 Sep 28;9(10):1343. doi: 10.3390/biomedicines9101343.

Giorgi C & Marinelli S. Roles and Transcriptional Responses of Inhibitory Neurons in Learning and Memory.Front Mol Neurosci. 2021 Jun 15;14:689952.

Hampel H, Caruso G, Nisticò R, Piccioni G, Mercuri NB, Giorgi FS, Ferrarelli F, Lemercier P, Caraci F, Lista S, Vergallo A. Biological Mechanism-based Neurology and Psychiatry: a BACE1/2 and Downstream Pathway Model. Curr Neuropharmacol. 2021 Nov 30. doi: 10.2174/1570159X19666211201095701.

Hampel H, Nisticò R, Seyfried NT, Levey AI, Modeste E, Lemercier P, Baldacci F, Toschi N, Garaci F, Perry G, Emanuele E, Valenzuela PL, Lucia A, Urbani A, Sancesario GM, Mapstone M, Corbo M, Vergallo A, Lista S. Alzheimer Precision Medicine Initiative (APMI). Omics sciences for systems biology in Alzheimer’s disease: State-of-the-art of the evidence. Ageing Res Rev. 2021 Aug;69:101346.  doi: 10.1016/j.arr.2021.101346.

Latina V, Giacovazzo G, Calissano P, Atlante A, La Regina F, Malerba F, Dell’Aquila M, Stigliano E, Balzamino BO, Micera A, Coccurello R, Amadoro G. Tau Cleavage Contributes to Cognitive Dysfunction in Strepto-Zotocin-Induced Sporadic Alzheimer’s Disease (sAD) Mouse Model. Int J Mol Sci. 2021 Nov 10;22(22):12158. doi: 10.3390/ijms222212158.

Latina V, Giacovazzo G, Cordella F, Balzamino BO, Micera A, Varano M, Marchetti C, Malerba F, Florio R, Ercole BB, La Regina F, Atlante A, Coccurello R, Di Angelantonio S, Calissano P, Amadoro G. Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer’s Disease. Acta Neuropathol Commun. 2021 Mar 9;9(1):38. doi: 10.1186/s40478-021-01138-1.

López-Ortiz S, Valenzuela PL, Seisdedos MM, Morales JS, Vega T, Castillo-García A, Nisticò R, Mercuri NB, Lista S, Lucia A, Santos-Lozano A. Exercise interventions in Alzheimer’s disease: A systematic review and meta-analysis of randomized controlled trials. Ageing Res Rev. 2021 Dec;72:101479. doi: 10.1016/j.arr.2021.101479. Epub 2021 Sep 30.PMID: 34601135

Malerba F, Arisi I, Florio R, Zecca C, Dell’Abate MT, Bruni Ercole B, Camerini S, Casella M, Logroscino G, Cattaneo A. proNGF Measurement in Cerebrospinal Fluid Samples of a Large Cohort of Living Patients With Alzheimer’s Disease by a New Automated Immunoassay. Front Aging Neurosci. 2021 Oct 27;13:741414. doi: 10.3389/fnagi.2021.741414. PMID: 34776928; PMCID: PMC8579109.

Malerba F, Bruni Ercole B, Florio R, Cattaneo A. A Quantitative Bioassay to Determine the Inhibitory Potency of NGF-TrkA Antagonists. SLAS Discov. 2021 Jul;26(6):823-830. doi: 10.1177/24725552211000672. Epub 2021 Apr 19. PMID: 33874771.

Mango D, Nisticò R. Neurodegenerative Disease: What Potential Therapeutic Role of Acid-Sensing Ion Channels? Front Cell Neurosci. 2021 Oct 8;15:730641. doi: 10.3389/fncel.2021.730641. eCollection 2021.

Nisticò R, Borg JJ. Aducanumab for Alzheimer’s disease: A regulatory perspective. Pharmacol Res. 2021 Sep;171:105754. doi: 10.1016/j.phrs.2021.105754. PMID: 34217830

Nisticò R, Pisani A. The treatment for Fabry disease: focus on agalsidase alpha and beta. Recenti Prog Med. 2021 Oct;112(10):75e-84e. doi: 10.1701/3679.36652.PMID: 34647542 Italian.

Pimpinella D,  Mastrorilli V, Giorgi C, Coemans S, Lecca S, Lalive AL, Ostermann H, Monyer H, Mele A, Cherubini E and Griguoli M (2021) Septal cholinergic input to CA2 hippocampal region controls social 1 memory via nicotinic receptor-mediated disinhibition. eLIFE Elife. 2021 Oct 26;10:e65580. doi: 10.7554/eLife.65580.

Sheean ME, Naumann-Winter F, Capovilla G, Kalland ME, Malikova E, Mariz S, Matusevicius D, Nistico R, Schwarzer-Daum B, Tsigkos S, Tzogani K, Larsson K, Magrelli A, Stoyanova-Beninska V. Defining Satisfactory Methods of Treatment in Rare Diseases When Evaluating Significant Benefit-The EU Regulator’s Perspective. Front Med (Lausanne). 2021 Aug 27;8:744625. eCollection 2021.PMID: 34513895.

Siano G, Falcicchia C, Origlia N, Cattaneo A, Di Primio C. Non-Canonical Roles of Tau and Their Contribution to Synaptic Dysfunction. Int J Mol Sci. 2021 Sep 20;22(18):10145. doi: 10.3390/ijms221810145. PMID: 34576308; PMCID: PMC8466023.

Testa G, Cattaneo A, Capsoni S. Understanding pain perception through genetic painlessness diseases: The role of NGF and proNGF. Pharmacol Res. 2021 Jul;169:105662. doi: 10.1016/j.phrs.2021.105662. Epub 2021 May 15. PMID: 34000361.

 

2020

Amodeo R, Convertino D, Calvello M, Ceccarelli L, Bonsignore F, Ravelli C, Cattaneo A, Martini C, Luin S, Mitola S, Signore G, Marchetti L. Fluorolabeling of the PPTase-Related Chemical Tags: Comparative Study of Different Membrane Receptors and Different Fluorophores in the Labeling Reactions. Front Mol Biosci. 2020 Aug 7;7:195. doi: 10.3389/fmolb.2020.00195. PMID: 32850976; PMCID: PMC7426934.

Arisi I, Mantuano E, “Age and gender distribution of COVID-19 infected cases in Italian population”, Research Square. Preprint 2020, https://assets.researchsquare.com/files/rs-72021/v1/e3e592bc-2d96-458a-98db-a0ae6712ff47.pdf?c=1631854633  

Badurek S*,  Griguoli M*, Zonta B, Fei G, Middei S, Lagostena L, Jurado-Parras MT, Gillingwater TH, Gruart A, Delgado-García JM, Cherubini E, Minichiello L (2020). Trkb deletion in immature dentate granule cells impairs hippocampal trisynaptic circuit and adult cognitive functions. iScience 23(5):101078. doi:10.1016/j.isci.2020.101078.

Buccarello L, Dragotto J, Iorio F, Hassanzadeh K, Corbo M and Feligioni M (2020). The pivotal role of SUMO-1-JNK-Tau axis in an in vitro model of oxidative stress counteracted by the protective effect of curcumin. Biochem Pharmacol 78:114066. doi:10.1016/j.bcp.2020.114066

Capovilla G, Nistico R, Magrelli A. (2020) Reply to the article “Management of status epilepticus in adults. Position paper of the Italian League against Epilepsy”. Epilepsy Behav. 2020 Jan 22:106866. doi: 10.1016/j.yebeh.2019.106866. [Epub ahead of print] PubMed PMID: 31982343.

Caputo V, Pacilli MG, Arisi I, Mazza T, Brandi R, Traversa A, Casasanta G, Pisa E, Sonnessa M, Healey B, Moggio L, D’Onofrio M, Alleva E, Macrì S. Genomic and physiological resilience in extreme environments are associated with a secure attachment style. Transl Psychiatry 2020; 10(1):185. Published 2020 Jun 9. doi:10.1038/s41398-020-00869-4

Cherubini E, Griguoli M (2019) GABAergic Signaling at Newborn Mossy Fiber–CA3 Synapses Short and Long-Term Activity-Dependent Synaptic Plasticity Processes. In Comprehensive Developmental Neuroscience, Rakic & Rubenstein Eds

Convertino D, Mishra N, Marchetti L, Calvello M, Viegi A, Cattaneo A, Fabbri F, Coletti C. Effect of Chemical Vapor Deposition WS2 on Viability and Differentiation of SH-SY5Y Cells. Front Neurosci. 2020 Oct 30;14:592502. doi: 10.3389/fnins.2020.592502. PMID: 33192279; PMCID: PMC7662391.

Corsetti V, Borreca A, Latina V, Giacovazzo G, Pignataro A, Krashia P, Natale F, Cocco S, Rinaudo M, Malerba F, Florio R, Ciarapica R, Coccurello R, D’Amelio M, Ammassari-Teule M, Grassi C, Calissano P, Amadoro G.Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer’s disease models. Brain Commun. 2020 Apr 6;2(1):fcaa039.

Di Segni M, D’Addario SL, Babicola L, Ielpo D, Lo Iacono L, Andolina D, Accoto A, Luchetti A, Mancini C, Parisi C, D’Onofrio M, Arisi I, Brandi R, Pascucci T, Cifani C, D’Amato FR, Ventura R (2020) Xlr4 as a new candidate gene underlying vulnerability to cocaine effects. Neuropharmacology. 2020;168:108019. doi:10.1016/j.neuropharm.2020.108019

Fantini M, Lisi S, De Los Rios P, Cattaneo A, Pastore A. Protein Structural Information and Evolutionary Landscape by In Vitro Evolution. Mol Biol Evol. 2020 Apr 1;37(4):1179-1192. doi: 10.1093/molbev/msz256. PMID: 31670785; PMCID: PMC7086169.

Gobbo F, Cattaneo A. Neuronal Activity at Synapse Resolution: Reporters and Effectors for Synaptic Neuroscience. Front Mol Neurosci. 2020 Oct 21;13:572312. doi: 10.3389/fnmol.2020.572312. PMID: 33192296; PMCID: PMC760988

Gorlewicz A, Barthet G, Zucca S, Vincent P, Griguoli M, Grosjean N, Wilczynski G, Mulle C (2021). The deletion of GluK2 alters cholinergic control of neuronal excitability. Cerebral Cortex doi:10.1093/cercor/bhab390

Hampel H, Vassar R, De Strooper B, Hardy J, Willem M, Singh N, Zhou J, Yan R, Vanmechelen E, De Vos A, Nisticò R, Corbo M, Imbimbo BP, Streffer J, Voytyuk I, Timmers M, Tahami Monfared AA, Irizarry M, Albala B, Koyama A, Watanabe N, Kimura T, Yarenis L, Lista S, Kramer L, Vergallo A. The β-Secretase BACE1 in Alzheimer’s Disease. Biol Psychiatry. 2020 Feb 13:S0006-3223(20)30063-9.

Hampel H, Caraci F, Cuello AC, Caruso G, Nisticò R, Corbo M, Baldacci F, Toschi N, Garaci F, Chiesa PA, Verdooner SR, Akman-Anderson L, Hernández F, Ávila J, Emanuele E, Valenzuela PL, Lucía A, Watling M, Imbimbo BP, Vergallo A, Lista S. A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer’s Disease. Front Immunol. 2020 Mar 31;11:456.

Hampel H, Vergallo A, Caraci F, Cuello AC, Lemercier P, Vellas B, Giudici KV, Baldacci F, Hänisch B, Haberkamp M, Broich K, Nisticò R, Emanuele E, Llavero F, Zugaza JL, Lucía A, Giacobini E, Lista S; Alzheimer Precision Medicine Initiative. Future avenues for Alzheimer’s disease detection and therapy: liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery. Neuropharmacology. 2020 May 11:108081.

Hassanzadeh, K, Perez Pena H, Dragotto, J, Buccarello L, Iorio F, Pieraccini S, Sancini G, Feligioni M (2020). Considerations around the SARS-CoV-2 Spike Protein with particular attention to COVID-19 brain infection and neurological symptoms. ACS Chemical Neuroscience 11:2361-2369.

Hassanzadeh K, Buccarello L, Dragotto J, Mohammadi A, Corbo M, Feligioni M (2020). Obstacles Against the marketing of Curcumin as a Drug.  Int. J. Mol. Sci 21(18):E6619. Published 2020 Sep 10. doi:10.3390/ijms21186619

Leal NS, Dentoni G, Schreiner B, Naia L, Piras A, Graff C, Cattaneo A, Meli G, Hamasaki M, Nilsson P, Ankarcrona M (2020). Amyloid beta-Peptide Increases Mitochondria-Endoplasmic Reticulum Contact Altering Mitochondrial Function and Autophagosome Formation in Alzheimer’s Disease-Related Models. CELLS, vol. 9, ISSN: 2073-4409, doi: 10.3390/cells9122552 IF (2020)

Lourenço J, De Stasi AM, Deleuze C, Bigot M, Pazienti A, Aguirre A, Giugliano M, Ostojic S, Bacci A (2020). Modulation of Coordinated Activity Across Cortical Layers by Plasticity of Inhibitory Synapses. Cell Rep 30:630-641.

Lupascu CA, Morabito A, Ruggeri F,  Parisi C, Pimpinella D, Pizzarelli R, Meli G, Marinelli S, Cherubini E, Cattaneo A, Migliore M (2020). Computational Modeling of Inhibitory Transsynaptic Signaling in Hippocampal and Cortical Neurons Expressing Intrabodies Against Gephyrin. Front Cell Neurosci 2020; 14:173. Published 2020 Jun 16; doi:10.3389/fncel.2020.00173.

Mango D, Nisticò R. Role of ASIC1a in Normal and Pathological Synaptic Plasticity. Rev Physiol Biochem Pharmacol. 2020;177:83-100. doi: 10.1007/112_2020_45.PMID: 32789788 Review.

Marangon D, Boda E, Parolisi R, Negri C, Giorgi C, Montarolo F, Perga S, Bertolotto A, Buffo A, Abbracchio MP, Lecca D (2020). In vivo silencing of miR-125a-3p promotes myelin repair in models of white matter demyelination. Glia 68:2001-2014.

Miraglia F, Valvano V, Rota L, Di Primio C, Quercioli V, Betti L, Giannaccini G, Cattaneo A, Colla E. Alpha-Synuclein FRET Biosensors Reveal Early Alpha-Synuclein Aggregation in the Endoplasmic Reticulum. Life (Basel). 2020 Aug 11;10(8):147. doi: 10.3390/life10080147. PMID: 32796544; PMCID: PMC7460339.

Nuzzo T, Miroballo M, Casamassa A, Mancini A, Gaetani L, Nisticò R, Eusebi P, Katane M, Homma H, Calabresi P, Errico F, Parnetti L, Usiello A. Cerebrospinal fluid and serum d-serine concentrations are unaltered across the whole clinical spectrum of Alzheimer’s disease. Biochim Biophys Acta Proteins Proteom. 2020 Dec;1868(12):140537. doi: 10.1016/j.bbapap.2020.140537. Epub 2020 Sep 5.PMID: 32896673

Pacilli MG, Arisi I, Mazza T, Brandi R, Traversa A, Casasanta G, Pisa E, Sonnessa M, Healey B, Moggio L, D’Onofrio M, Alleva E, Macrì S, “Genomic and physiological resilience in extreme environments are associated with a secure attachment style”, Transl Psych, 2020 Jun 9;10(1):185. doi: 10.1038/s41398-020-00869-4

Petrella C, Farioli-Vecchioli S, Cisale GY, Strimpakos G, Borg JJ, Ceccanti M, Fiore M, Monteleone G, Nisticò R. A healthy gut for a healthy brain: preclinical, clinical and regulatory aspects. Curr Neuropharmacol. 2020 Jul 30. doi: 10.2174/1570159X18666200730111528.

Petrella C, Ciotti MT, Nisticò R, Piccinin S, Calissano P, Capsoni S, Mercanti D, Cavallaro S, Possenti R, Severini C. Involvement of Bradykinin Receptor 2 in Nerve Growth Factor Neuroprotective Activity. Cells. 2020 Dec 10;9(12):2651. doi: 10.3390/cells9122651.PMID: 33321704 

Pizzarelli R, Griguoli M, Zacchi P, Petrini EM, Barberis A, Cattaneo A,  Cherubini E (2020). Gephyrin functions at inhibitory synapses: new advances and future perspectives. Neuroscience 439:125-136 (special number in honor of R. Miledi).

Rizzello E, Middei S, Marchetti C (2020) Synaptic Correlates of Anterograde Amnesia and Intact Retrograde Memory in a Mouse Model of Alzheimer’s Disease. Current Alzheimer Research, 17: 259-268.

Rossi S, Rompietti V, Antonucci Y, Giovannini D, Scopa C, Scaricamazza S, Scardigli R, Cestra G, Serafino A, Carrì MT, D’Ambrosi N, Cozzolino M. (2020). UsnRNP Trafficking Is Regulated by Stress Granules and Compromised by Mutant ALS Proteins. Neurobiology of Disease 138: 104792.

Scopa C, Marrocco F, Latina V, Ruggeri F, Corvaglia V, La Regina F, Ammassari-Teule M, Middei S, Amadoro G, Meli G, Scardigli R, Cattaneo A. (2020). Impaired adult neurogenesis is an early event in Alzheimer’s disease neurodegeneration, mediated by intracellular Ab oligomers. Cell Death and Differentiation  27: 934-948.

Siano G, Micaelli M, Scarlatti A, Quercioli V, Di Primio C, Cattaneo A. The Q336H MAPT Mutation Linked to Pick’s Disease Leads to Increased Binding of Tau to the Microtubule Network via Altered Conformational and Phosphorylation Effects. Front Mol Neurosci. 2020 Dec 2;13:569395. doi: 10.3389/fnmol.2020.569395. PMID: 33343296; PMCID: PMC7738341.

Singh AS, Takhellambam MC, Cappelletti P, Feligioni M (2020). Immediate Early Gene Kakusei Potentially Plays a Role in the Daily Foraging of Honey Bees. PLoS One 15(5):e0222256. Published 2020 May 6. doi:10.1371/journal.pone.0222256

Soligo M, Protto V, Chiaretti A, Piccinin S, De Stefano ME, Nisticò R, Bracci-Laudiero L, Manni L. Effects of intranasally-delivered pro-nerve growth factors on the septo-hippocampal system in healthy and diabetic rats. Neuropharmacology. 2020 Jul 15;176:108223.

 

2019

Arisi I, D’Onofrio M, Brandi, R, Sonnessa M, Campanelli A, Florio R, Sposato V, Malerba F, Cattaneo A, Mecocci P, Bruno G, Canevelli M, Tsolaki M, Pelteki N, Stocchi F, Vacca L, Fiscon G, Bertolazzi P (2019). Mining clinical and laboratory data of neurodegenerative diseases by Machine Learning: transcriptomic biomarkers”, Proceedings – 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. 21 January 2019, Article number 8621072, Pages 2735-2737

Bonfiglio T, Olivero G, Vergassola M, Di Cesare Mannelli L, Pacini A,Iannuzzi F, Summa M, Bertorelli R, Feligioni M,Ghelardini C, Pittaluga A (2019). Environmental training is beneficial to clinical symptoms and cortical presynaptic defects in mice suffering from experimental autoimmune encephalomyelitis. Neuropharmacology 145:75-86.

Casagrande V, Mauriello A, Anemona L, Mavilio M, Iuliani G, De Angelis L, D’Onofrio M, Arisi I, Federici M, Menghini R (2019). Timp3 deficiency affects the progression of DEN-related hepatocarcinoma during diet-induced obesity in mice. Acta Diabetol  56:1265–1274.

Cattaneo A, Capsoni S. Painless Nerve Growth Factor: A TrkA biased agonist mediating a broad neuroprotection via its actions on microglia cells. Pharmacol Res. 2019 Jan;139:17-25. doi: 10.1016/j.phrs.2018.10.028. Epub 2018 Nov 1. PMID: 30391352.

Cattaneo A, Chirichella M. Targeting the Post-translational Proteome with Intrabodies. Trends Biotechnol. 2019 Jun;37(6):578-591. doi: 10.1016/j.tibtech.2018.11.009. Epub 2018 Dec 18. PMID: 30577991.

Corvaglia V, Cilli D, Scopa C, Brandi R, Arisi I, Malerba F, La Regina F, Scardigli R and Cattaneo A (2019). ProNGF is a cell-type specific mitogen for adult hippocampal and for induced neural stem cells. Stem Cells 37:1223–1237.

Deleuze C, Bhumbra GS, Pazienti A, Lourenço J, Mailhes C, Aguirre A, Beato M, Bacci A (2019). Strong preference for autaptic self-connectivity of neocortical PV interneurons facilitates their tuning to γ-oscillations. PLoS Biol 17(9):e3000419. Published 2019 Sep 4. doi:10.1371/journal.pbio.3000419

Hampel H, Lista S, Mango D, Nisticò R, Perry G, Avila J, Hernandez F, Geerts H, Vergallo A (2019). Alzheimer Precision Medicine Initiative (APMI). Lithium as a Treatment for Alzheimer’s Disease: The Systems Pharmacology Perspective. J Alzheimers Dis 69:615-629.

Mango D, Caruso A, Saidi A, Nisticò R, Scaccianoce S (2019). The positive allosteric modulator at mGlu2 receptors, LY487379, reverses the effects of chronic stress-induced behavioral maladaptation and synaptic dysfunction in the adulthood. Synapse Apr 9. doi: 10.1002/syn.22101.

Mango D, Nisticò R. (2019). Acid-Sensing Ion Channel 1a Is Involved in N-Methyl D-Aspartate Receptor-Dependent Long-Term Depression in the Hippocampus. Front Pharmacol May 21;10:555. doi: 10.3389/fphar.2019.00555. eCollection 2019.

Mango D, Nisticò R, Furlan R, Finardi A, Centonze D, Mori F. PDGF Modulates Synaptic Excitability and Short-Latency Afferent Inhibition in Multiple Sclerosis. Neurochem Res. 2019 Mar;44(3):726-733.

Mango D, Saidi A, Cisale GY, Feligioni M, Corbo M, Nisticò R (2019). Targeting Synaptic Plasticity in Experimental Models of Alzheimer’s Disease. Front Pharmacol 2019 Jul 16;10:778. doi: 10.3389/fphar.2019.00778. eCollection 2019. Review.

Marcelli S, Iannuzzi F, Ficulle E, Mango D, Pieraccini S, Pellegrino S, Corbo M, Sironi M, Pittaluga A, Nisticò R, Feligioni M. (2019). The selective disruption of presynaptic JNK2/STX1a interaction reduces NMDA receptor-dependent glutamate release. Sci Rep. 2019 May 9;9(1):7146. doi: 10.1038/s41598-019-43709-2.  

Marchetti L, Bonsignore F, Gobbo F, Amodeo R, Calvello M, Jacob A, Signore G, Schirripa Spagnolo C, Porciani D, Mainardi M, Beltram F, Luin S, Cattaneo A. Fast-diffusing p75NTR monomers support apoptosis and growth cone collapse by neurotrophin ligands. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21563-21572. doi: 10.1073/pnas.1902790116. Epub 2019 Sep 12. PMID: 31515449; PMCID: PMC6815156.

Marinelli S, Basilico B, Marrone MC, Ragozzino D. Microglia-neuron crosstalk: Signaling mechanism and control of synaptic transmission. Semin Cell Dev Biol. 2019 May 30. pii: S1084-9521(18)30170-8. doi: 10.1016/j.semcdb.2019.05.017.

Mehrez F, Bougatef K, Delle Monache E, Arisi I, Proietti-De-Santis L, Prantera G, Zouiten Mekki L, Caputo M, Benammar Elgaaïed E, Bongiorni Santis (2019). Telomere length measurement in tumor and non-tumor cells as a valuable prognostic for tumor progression. Cancer Genetics, 238: 50-61.

Micheli L, D’Andrea G, Ceccarelli M, Ferri A, Scardigli R, Tirone F (2019). p16Ink4a Prevents the Activation of Aged Quiescent Dentate Gyrus Stem Cells by Physical Exercise. Front Cell Neurosci 2019 Feb 7;13:10. doi: 10.3389/fncel.2019.00010. eCollection 2019.

Modi B, Pimpinella D, Pazienti A, Zacchi P, Cherubini E, Griguoli M (2019). Possible Implication of the CA2 Hippocampal Circuit in Social Cognition Deficits Observed in the Neuroligin 3 Knock-Out Mouse, a Non-Syndromic Animal Model of Autism. Front Psychiatry 10:513. doi: 10.3389/fpsyt.2019.00513.

Nicolis di Robilant V, Scardigli R, Strimpakos G, Tirone F, Middei S, Scopa C, De Bardi M, Battistini L, Saraulli D, Farioli-Vecchioli S (2019). Running-Activated Neural Stem Cells Enhance Subventricular Neurogenesis and Improve Olfactory Behavior in p21 Knockout Mice. Mol Neurobiol  May 6. doi: 10.1007/s12035-019-1590-6.

Nuzzo T, Feligioni M, Cristino L, Pagano I, Marcelli S, Iannuzzi F, Imperatore R, D’Angelo L, Petrella C, Carella M, Pollegioni L, Sacchi S, Punzo D, De Girolamo P, Errico F, Canu N, Usiello A (2019). Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity. Exp Neurol  317:51-65.

Pandolfini L, Barbieri I, Bannister AJ, Hendrick A, Andrews B, Webster N, Murat P, Mach P, Brandi R, Robson SC, Migliori V, Alendar A, d’Onofrio M, Balasubramanian S, Kouzarides T (2019). METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Mol Cell 74:1278-1290.

Pignataro A,  Meli G, Pagano R, Fontebasso V, Battistella R, Conforto G, Ammassari-Teule M, Middei S (2019). Activity-induced Aβ oligomers drive compensatory synaptic rearrangements in brain circuits controlling memory of pre-symptomatic AD mice. Biological Psychiatry 86:185-195.

Piscopo P, Lacorte E, Feligioni M, Mayer F, Crestini A, Piccolo L, Bacigalupo I, Filareti M, Ficulle E, Confaloni A, Vanacore N, Corbo M (2019). MicroRNAs and mild cognitive impairment: A systematic review. Ageing Res Rev  50:131-141

Pizzarelli R, Griguoli M, Zacchi P, Petrini EM, Barberis A, Cattaneo A and Cherubini E (2019). Tuning

GABAergic inhibition: gephyrin molecular organization and functions. Neuroscience 4522: 30520-3052. DOI: 10.1016/j.neuroscience.2019.07.036. Review article.

Protto V, Soligo M, De Stefano ME, Farioli-Vecchioli S, Marlier LNJL, Nisticò R, Manni L (2019). Electroacupuncture in rats normalizes the diabetes-induced alterations in the septo-hippocampal cholinergic system. Hippocampus 29:891-904.

Rinaldi L, Delle Donne R, Catalanotti B, Torres-Quesada O, Enzler F, Moraca F, Nisticò R, Chiuso F, Piccinin S, Bachmann V, Lindner HH, Garbi C, Scorziello A, Russo NA, Synofzik M, Stelzl U, Annunziato L, Stefan E, Feliciello A (2019). Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system. Nat Commun Jun 12;10(1):2572. doi: 10.1038/s41467-019-10037-y.

Rota L, Pellegrini C, Benvenuti L, Antonioli L, Fornai M, Blandizzi C, Cattaneo A, Colla E. Constipation, deficit in colon contractions and alpha-synuclein inclusions within the colon precede motor abnormalities and neurodegeneration in the central nervous system in a mouse model of alpha-synucleinopathy. Transl Neurodegener. 2019 Feb 6;8:5. doi: 10.1186/s40035-019-0146-z. PMID: 30774946; PMCID: PMC6364448.

Russo A, Scardigli R, La Regina F, Murray ME, Romano N, Dickson DW, Wolozin B, Cattaneo A, Ceci M. Corrigendum: Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes. Hum Mol Genet. 2019 Apr 1;28(7):1226. doi: 10.1093/hmg/ddy407. Erratum for: Hum Mol Genet. 2017 Apr 15;26(8):1407-1418. PMID: 30541120; PMCID: PMC6423413.

Sarkar, Atay Y, Erickson AL, Arisi I, Saltini C, Kahveci T (2019). An efficient algorithm for identifying mutated subnetworks associated with survival in cancer. IEEE/ACM Trans Comput Biol Bioinform Apr 15. doi: 10.1109/TCBB.2019.2911069.

Siano G, Varisco M, Caiazza MC, Quercioli V, Mainardi M, Ippolito C, Cattaneo A, Di Primio C. Tau Modulates VGluT1 Expression. J Mol Biol. 2019 Feb 15;431(4):873-884. doi: 10.1016/j.jmb.2019.01.023. Epub 2019 Jan 18. PMID: 30664870.

Siano G, Caiazza MC, Varisco M, Calvello M, Quercioli V, Cattaneo A, Di Primio C. Modulation of Tau Subcellular Localization as a Tool to Investigate the Expression of Disease-related Genes. J Vis Exp. 2019 Dec 20;(154). doi: 10.3791/59988. PMID: 31904014.

Siano G, Caiazza MC, Ollà I, Varisco M, Madaro G, Quercioli V, Calvello M, Cattaneo A, Di Primio C. Identification of an ERK Inhibitor as a Therapeutic Drug Against Tau Aggregation in a New Cell-Based Assay. Front Cell Neurosci. 2019 Aug 21;13:386. doi: 10.3389/fncel.2019.00386. PMID: 31496937; PMCID: PMC6712076.

Testa G, Calvello M, Cattaneo A, Capsoni S. Cholinergic striatal neurons are increased in HSAN V homozygous mice despite reduced NGF bioavailability. Biochem Biophys Res Commun. 2019 Feb 12;509(3):763-766. doi: 10.1016/j.bbrc.2018.12.178. Epub 2019 Jan 3. PMID: 30612733.

Testa G, Mainardi M, Morelli C, Olimpico F, Pancrazi L, Petrella C, Severini C, Florio R, Malerba F, Stefanov A, Strettoi E, Brandi R, Arisi I, Heppenstall P, Costa M, Capsoni S, Cattaneo A. The NGFR100W mutation specifically impairs nociception without affecting cognitive performance in a mouse model of Hereditary Sensory and Autonomic Neuropathy type V. J Neurosci. 2019 Nov 4. pii: 0688-19. doi: 10.1523/JNEUROSCI.0688-19.2019

Testa G, Olimpico F, Pancrazi L, Borello U, Cattaneo A, Caleo M, Costa M, Mainardi M. Cortical Seizures in FoxG1+/- Mice are Accompanied by Akt/S6 Overactivation, Excitation/Inhibition Imbalance and Impaired Synaptic Transmission. Int J Mol Sci. 2019 Aug 24;20(17):4127. doi: 10.3390/ijms20174127. PMID: 31450553; PMCID: PMC6747530.

Tinelli C, Di Pino A, Ficulle E, Marcelli S, Feligioni M (2019). Hyperhomocysteinemia as a Risk Factor and Potential Nutraceutical Target for Certain Pathologies. Front Nutr Apr 24;6:49. doi: 10.3389/fnut.2019.00049.

Torromino G, Autore L, Khalil V, Mastrorilli V, Griguoli M, Pignataro A, Centofante E, Biasini GM, De Turris V, Ammassari-Teule M, Rinaldi A, Mele A (2019). Offline ventral subiculum-ventral striatum serial communication is required for spatial memory consolidation. Nat Commun  Dec 16;10(1):5721. doi: 10.1038/s41467-019-13703-3.

Vetere G, Borreca A, Pignataro A, Conforto G, Giustizieri M, Marinelli S, Ammassari-Teule M. Coincident Pre- and Post-Synaptic Cortical Remodelling Disengages Episodic Memory from Its Original Context. Mol Neurobiol. 2019 Jul 2. doi: 10.1007/s12035-019-01652-3.

Yan R, Yalinca H, Paoletti F, Gobbo F, Marchetti L, Kuzmanic A, Lamba D, Gervasio FL, Konarev PV, Cattaneo A, Pastore A. The Structure of the Pro-domain of Mouse proNGF in Contact with the NGF Domain. Structure. 2019 Jan 2;27(1):78-89.e3. doi: 10.1016/j.str.2018.09.013. Epub 2018 Nov 1. PMID: 30393051.

 

2018

Borreca A, Latina V, Corsetti V, Middei S, Piccinin S, Della Valle F, Bussani R, Ammassari-Teule M, Nisticò R, Calissano P, Amadoro G (2018). AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy. Mol Neurobiol  55:8124-8153.

Colla E, Panattoni G, Ricci A, Rizzi C, Rota L, Carucci N, Valvano V, Gobbo F, Capsoni S, Lee MK, Cattaneo A (2018) . Toxic properties of microsome-associated alpha-synuclein species in mouse primary neurons. Neurobiol Dis. 2018 Mar;111:36-47. doi: 10.1016/j.nbd.2017.12.004. Epub 2017 Dec 12.

Criscuolo C, Cerri E, Fabiani C, Capsoni S, Cattaneo A, Domenici L. (2018) The retina as a window to early dysfunctions of Alzheimer’s disease following studies with a 5xFAD mouse model. Neurobiol Aging. 67:181-188. doi:10.1016/j.neurobiolaging.2018.03.017. Epub 2018 Mar 23

Ficulle E, Sufian MDS, Tinelli C, Corbo M, Feligioni M (2018). Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice. Neurosci Lett 668:48-54.

Gobbo F, Bonsignore F, Amodeo R, Cattaneo A, Marchetti L. (2018) Site-Specific Direct Labeling of Neurotrophins and Their Receptors: From Biochemistry to Advanced Imaging Applications.  Methods Mol Biol. 2018;1727:295-314. doi: 10.1007/978-1-4939-7571-6_22.

Hampel H, Toschi N, Babiloni C, Baldacci F, Black KL, Bokde ALW, Bun RS, Cacciola F, Cavedo E, Chiesa PA, Colliot O, Coman CM, Dubois B, Duggento A, Durrleman S, Ferretti MT, George N, Genthon R, Habert MO, Herholz K, Koronyo Y, Koronyo-Hamaoui M, Lamari F, Langevin T, Lehéricy S, Lorenceau J, Neri C, Nisticò R, Nyasse-Messene F, Ritchie C, Rossi S, Santarnecchi E, Sporns O, Verdooner SR,  Vergallo A, Villain N, Younesi E, Garaci F, Lista S (2018). Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology. J Alzheimers Dis 64:S47-S105. doi:10.3233/JAD-179932

Hampel H, Vergallo A, Giorgi FS, Kim SH, Depypere H, Graziani M, Saidi A, Nisticò R, Lista S (2018). Precision medicine and drug development in Alzheimer’s disease: the importance of sexual dimorphism and patient stratification. Front Neuroendocrinol 2018;50:31-51. 

Ledonne A, Mango D, Latagliata EC, Chiacchierini G, Nobili A, Nisticò R, D’Amelio M, Puglisi-Allegra S, Mercuri NB (2018). Neuregulin 1/ErbB signalling modulates hippocampal mGluRI-dependent LTD and object recognition memory. Pharmacol Res  130:12-24.

Lee J*, Arisi I*,Puxeddu E, Mramba L, Amicosante M, Swaigswood C, Brantly M, Pallante M, Skold M, Saltini C (2018). Bronchoalveolar lavage (BAL) cells in Idiopathic Pulmonary Fibrosis express a complex pro-inflammatory, pro-repair, angiogenic activation pattern, likely associated with macrophage iron accumulation. PLoS One May 17;13(5):e0197794.

Maccarrone M, Totaro A, Leuti A, Giacovazzo G, Scipioni L, Mango D, Coccurello R, Nisticò R, Oddi S. (2018). Early alteration of distribution and activity of hippocampal type-1 cannabinoid receptor in Alzheimer’s disease-like mice overexpressing the human mutant amyloid precursor protein. Pharmacol Res  130:366-373.  

Mango D, Nisticò R. (2018). Role of ASIC1a in Aβ-induced synaptic alterations in the hippocampus. Pharmacol Res 131:61-65.

Mango D, Nisticò R, Furlan R, Finardi A, Centonze D, Mori F. (2018). PDGF Modulates Synaptic Excitability and Short-Latency Afferent Inhibition in Multiple Sclerosis. Neurochem Res Feb 1. doi: 10.1007/s11064-018-2484-0.

Marcelli S, Corbo M, Iannuzzi F, Negri L, Blandini F, Nisticò R, Feligioni M (2018). The involvement of post-translational modifications in Alzheimer’s disease. Curr Alzheimer Res 15:313-335. 

Marcelli S, Ficulle E, Piccolo L, Corbo M, Feligioni M (2018). An overview of the possible therapeutic role of SUMOylation in the treatment of Alzheimer’s disease. Pharmacol Res 130:420-437.

Medelin M, Porrelli D, Aurand ER, Scaini D, Travan A, Borgogna MA, Cok M, Donati I, Marsich E, Scopa C, Scardigli R, Paoletti S, Ballerini L (2018). Exploiting natural polysaccharides to enhance in vitro bio-constructs of primary neurons and progenitor cells. Acta Biomater doi: 10.1016/j.actbio.2018.03.041. Epub 2018 Apr 3.

Nardecchia F, Orlando R, Iacovelli L, Colamartino M, Fiori E, Leuzzi V, Piccinin S, Nistico R, Puglisi-Allegra S, Di Menna L, Battaglia G, Nicoletti F, Pascucci T (2018). Targeting mGlu5 Metabotropic Glutamate Receptors in the Treatment of Cognitive Dysfunction in a Mouse Model of Phenylketonuria. Front Neurosci Mar 16;12:154. doi: 10.3389/fnins.2018.00154. 

Nisticò R, Peineau S (2018). Alzheimer’s disease: understanding homeostasis deregulation to foster development of effective therapies. Pharmacol Res 139:467-468.

Paolantoni C, Ricciardi S, De Paolis V, Okenwa C, Catalanotto C, Ciotti MT, Cattaneo A, Cogoni C, Giorgi C (2018). Arc 3′ UTR Splicing Leads to Dual and Antagonistic Effects in Fine-Tuning Arc Expression Upon BDNF Signaling. Front Mol Neurosci doi:10.3389/fnmol.2018.00145.

Rizzi C, Tiberi A, Giustizieri M, Marrone MC, Gobbo F, Carucci N, Meli G, Arisi I, D’Onofrio M, Marinelli S, Capsoni S, Cattaneo A (2018). NGF steers microglia towards a neuroprotective phenotype. Glia  66:1395-1416.

Sancesario GM, Nuccetelli M, Cerri A, Zegeer J, Severini C, Ciotti MT, Pieri  M, Martorana A, Caltagirone C, Nisticò R, Bernardini S (2018). Bromelain Degrades Aβ1-42 Monomers and Soluble Aggregates: An In Vitro Study in Cerebrospinal Fluid of Alzheimer’s Disease Patients. Curr Alzheimer Res 15:628-636.

Sanguanini M, Cattaneo A. A continuous model of physiological prion aggregation suggests a role for Orb2 in gating long-term synaptic information. R Soc Open Sci. 2018 Dec 12;5(12):180336. doi: 10.1098/rsos.180336. PMID: 30662713; PMCID: PMC6304141.

Terrigno M, Busti I, Alia C, Pietrasanta M, Arisi I, D’Onofrio M, Caleo M, Cremisi F (2018). Neurons generated by mouse ES cell with hippocampal or cortical identity display distinct projection patterns when co-transplanted in the adult brain. Stem Cell Rep 10:1016-1029

 

2017

Allegra M, Spalletti C, Vignoli B, Azzimondi S, Busti I, Billuart P, Canossa M, Caleo M (2017). Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability. Neurobiol Dis 100:75-86.

Ambrosini A, D’Onofrio M, Buzzi MG, Arisi I, Grieco GS, Pierelli F, Santorelli FM, Schoenen J (2017). Possible Involvement of the CACNA1E Gene in Migraine: A Search for Single Nucleotide Polymorphism in Different Clinical Phenotypes. Headache 57:1136-1144.

Antonelli M, Strappazzon F, Arisi I, Brandi R, D’Onofrio M, Sambucci M, Manic G, Vitale I, Barilà D, Stagni V (2017). ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy. Oncotarget 8:21692-21709. 

Avvisati R, Meringolo M, Stendardo E, Malavasi E, Marinelli S, Badiani A (2017). Intravenous self-administration of benzydamine, a non-steroidal anti-inflammatory drug with a central cannabinoidergic mechanism of action. Addict Biol Apr 21. doi: 10.1111/adb.12516.

Baumgart M, Barth E, Savino A, Groth M, Koch P, Petzold A, Arisi I, Platzer M, Marz M, Cellerino A. A (2017). miRNA catalogue and ncRNA annotation of the short-living fish Nothobranchius furzeri. BMC Genomics 18:693. doi: 10.1186/s12864-017-3951-8.

Bucci, R., D, P., Iannuzzi, F., Feligioni, M., Gandolfi, R., Gelmi, M.L., Reches, M., Pellegrino, S (2017). Self-assembly of an amphipathic ααβ-tripeptide into cationic spherical particles for intracellular delivery. Org Biomol Chem 15:6773-6779.

Caioli S, Severini C, Ciotti T, Florenzano F, Pimpinella D, Petrocchi Passeri P, Balboni G, Polisca P, Lattanzi R, Nisticò R, Negri L, Zona C (2017). Prokineticin system modulation as a new target to counteract the amyloid beta toxicity induced by glutamatergic alterations in an in vitro model of Alzheimer’s disease. Neuropharmacology 116:82-97.

Capsoni S, Malerba F, Carucci NM, Rizzi C, Criscuolo C, Origlia N, Calvello M, Viegi A, Meli G, Cattaneo A (2017). The chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor. Brain 140 :201-217.

Caputo M, Balzerano A, Arisi I, D’Onofrio M, Brandi R, Bongiorni S, Brancorsini S, Frontini M, Proietti-De-Santis L (2017). CSB ablation induced apoptosis is mediated by increased endoplasmic reticulum stress response. PLoS One Mar 2;12(3):e0172399. doi: 10.1371/journal.pone.0172399.

Chirichella M, Lisi S, Fantini M, Goracci M, Calvello M, Brandi R, Arisi I, D’Onofrio M, Di Primio C, Cattaneo A (2017). Post-translational selective intracellular silencing of acetylated proteins with de novo selected intrabodies. Nat Methods 14:279-282.

De Jaco A, Mango D, De Angelis F, Favaloro FL, Andolina D, Nisticò R, Fiori E, Colamartino M, Pascucci T (2017). Unbalance between Excitation and Inhibition in Phenylketonuria, a Genetic Metabolic Disease Associated with Autism. Int J Mol Sci 2017 Apr 29;18(5). pii: E941. doi: 10.3390/ijms18050941.

Di Matteo P, Calvello M, Luin S, Marchetti L, Cattaneo A. (2017) An optimized procedure for the site-directed labeling of NGF and proNGF for imaging purposes. Front Mol Biosci. 2017 Feb 2;4:4. doi: 10.3389/fmolb.2017.00004.

Di Primio C, Quercioli V, Siano G, Rovere M, Kovacech B, Novak M, Cattaneo A.(2017) The distance between N and C termini of Tau and FTDP-17 mutants is modulated by microtubule interactions in living cells. Front Mol Neurosci. 10:210. doi: 10.3389/fnmol.2017.00210. eCollection 2017

Fantini M, Pandolfini L, Lisi S, Chirichella M, Arisi I, Terrigno M, Goracci M, Cremisi F, Cattaneo A (2017). Assessment of antibody library diversity through next generation sequencing and technical error compensation. PLoS One May 15;12(5):e0177574. doi: 10.1371/journal.pone.0177574. 

Fasulo L, Brandi R, Arisi I, La Regina F, Berretta N, Capsoni S, D’Onofrio M, Cattaneo A (2017). ProNGF Drives Localized and Cell Selective Parvalbumin Interneuron and Perineuronal Net Depletion in the Dentate Gyrus of Transgenic Mice. Front Mol Neurosci Feb 9;10:20. doi: 10.3389/fnmol.2017.00020. 

Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Sciacca MFM, Sinopoli A, Milardi D, Pappalardo G, De Spirito M, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G (2017). Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer’s disease and other tauopathies. Oncotarget 8:64745-64778.

Gobbo F, Marchetti L, Jacob A, Pinto B, Binini N, Pecoraro Bisogni F, Alia C, Luin S, Caleo M, Fellin T, Cancedda L and Cattaneo A (2017)  Activity-dependent expression of Channelrhodopsin at neuronal synapses. Nature Comm. 8, 1629. DOI: 10.1038/s41467-017-01699-7. Highlighted in Nature Comm

Griguoli M, Cherubini E (2017) Early Correlated Network Activity in the Hippocampus: Its Putative Role in Shaping Neuronal Circuits. Front Cell Neurosci Aug 22;11:255. doi: 10.3389/fncel.2017.00255.

Guglielmi L, Nardella M, Musa C, Iannetti I, Arisi I, D’Onofrio M, Storti A, Valentini A, Cacci E, Biagioni S, Augusti-Tocco G, D’Agnano I, Felsani A (2017). Lamin A/C Is Required for ChAT-Dependent Neuroblastoma Differentiation. Mol Neurobiol 54:3729-3744

Lista S, Toschi N, Baldacci F, Zetterberg H, Blennow K, Kilimann I, Teipel SJ, Cavedo E, Dos Santos AM, Epelbaum S, Lamari F, Dubois B, Nisticò R, Floris R, Garaci F, Hampel H (2017). Alzheimer Precision Medicine Initiative (APMI). Cerebrospinal Fluid Neurogranin as a Biomarker of Neurodegenerative Diseases: A Cross-Sectional Study. J Alzheimers Dis 59:1327-1334

Mancini F, Teveroni E, Di Conza G, Monteleone V, Arisi I, Pellegrino M, Buttarelli M, Pieroni L, D’Onofrio M, Urbani A, Pontecorvi A, Mazzone M, Moretti F (2017). MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability. Mol Cancer Mar 7;16(1):55. doi: 10.1186/s12943-017-0626-7.

Mango D, Braksator E, Battaglia G, Marcelli S, Mercuri NB, Feligioni M, Nicoletti F, Bashir ZI, Nisticò R (2017). Acid-sensing ion channel 1a is required for mGlu receptor dependent long-term depression in the hippocampus. Pharmacol Res 119:12-19. 

Marcelli S, Ficulle E, Iannuzzi F, Kövari E, Nisticò R, Feligioni M (2017). Targeting SUMO-1ylation Contrasts Synaptic Dysfunction in a Mouse Model of Alzheimer’s Disease. Mol Neurobiol  54:6609-6623. 

Marrone MC, Morabito A, Giustizieri M, Chiurchiù V, Leuti A, Mattioli M, Marinelli S, Riganti L, Lombardi M, Murana E, Totaro A, Piomelli D, Ragozzino D, Oddi S, Maccarrone M, Verderio C, Marinelli S (2017). TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice. Nat Commun May 10;8:15292. doi: 10.1038/ncomms15292.  

Mastrorilli V, Scopa C, Saraulli D, Costanzi M, Scardigli R, Rouault JP, Farioli-Vecchioli S, Tirone F (2017). Physical exercise rescues defective neural stem cells and neurogenesis in the adult subventricular zone of Btg1 knockout mice. Brain Struct Funct 222:2855-2876.

Nisticò R, Salter E, Nicolas C, Feligioni M, Mango D, Bortolotto ZA, Gressens P, Collingridge GL, Peineau S (2017). Synaptoimmunology – roles in health and disease. Mol Brain  10(1):26. Published 2017 Jun 20. doi:10.1186/s13041-017-0308-9. 

Russo A, Scardigli R, La Regina F, Murray ME, Romano N, Dickson DW, Wolozin B, Cattaneo A, Ceci M (2017). Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes. Hum Mol Genet 26:1407-1418. 

Sasi M, Vignoli B, Canossa M, Blum R (2017). Neurobiology of local and intercellular BDNF signaling. Pflugers Arch 469:593-610. 

Severini C, Petrocchi Passeri P, Ciotti MT, Florenzano F, Petrella C, Malerba F, Bruni B, D’Onofrio M, Arisi I, Brandi R, Possenti R, Calissano P, Cattaneo A (2017). Nerve growth factor derivative NGF61/100 promotes outgrowth of primary sensory neurons with reduced signs of nociceptive sensitization. Neuropharmacology 117:134-148.

Soligo M, Piccinin S, Protto V, Gelfo F, De Stefano ME, Florenzano F, Berretta E, Petrosini L, Nisticò R, Manni L (2017). Recovery of hippocampal functions and modulation of muscarinic response by electroacupuncture in young diabetic rats. Sci Rep Aug 22;7(1):9077. doi: 10.1038/s41598-017-08556-z. 

Weisz F, Piccinin S, Mango D, Ngomba RT, Mercuri NB, Nicoletti F, Nisticò R (2017). The role of adiponectin receptors in the regulation of synaptic transmission in the hippocampus. Synapse May;71(5). doi: 10.1002/syn.21964.

Zucca S*, Griguoli M*, Malézieux M, Grosjean N, Carta M, Mulle C (2017). Control of spike transfer at hippocampal mossy fiber synapses in vivo by GABAA and GABAB receptor mediated inhibition. Journal of Neuroscience, 37(3):587-598. *equally contributing authors

 

2016

Antonelli R, De Filippo R, Middei S, Stancheva S, Pastore B, Ammassari-Teule M, Barberis A, Cherubini E and Paola Zacchi (2016). Pin1 modulates the synaptic content of NMDA receptors via prolyl-isomerization of PSD-95. J Neurosci 36:5437-547.

Capsoni S, Malerba F, Carucci N, Rizzi C, Criscuolo C, Origlia N, Calvello MA, Viegi A, Meli G and Cattaneo A (2016) The chemokine CXCL12 mediates the anti-amyloidogenic actions of painless human Nerve Growth Factor.   BRAIN 140 (1): 201-217. doi:https://doi.org/10.1093/brain/aww271 Editorial highlight

Cellot G, Maggi L, Di Castro MA, Catalano M, Migliore R, Migliore M, Scattoni ML, Calamandrei G and Cherubini E (2016). Premature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice. Sci. Rep 6, 31696; doi: 10.1038/srep31696.

D’Aurizio R, Russo F, Chiavacci E, Baumgart M, Groth M, D’Onofrio M, Arisi I, Rainaldi G, Pitto L, Pellegrini M (2016). Discovering miRNA Regulatory Networks in Holt-Oram Syndrome Using a Zebrafish Model. Front Bioeng Biotechnol 2016;4:60. Published 2016 Jul 14. doi:10.3389/fbioe.2016.00060 

De Arcangelis V, Strimpakos G, Gabanella F, Corbi N, Luvisetto S, Magrelli A, Onori A, Passananti C, Pisani C, Rome S, Severini C, Naro F, Mattei E, Di Certo MG, Monaco L (2016). Pathways Implicated in Tadalafil Amelioration of Duchenne Muscular Dystrophy. J Cell Physiol  231:224-232. 

De Nadai T, Marchetti L, Di Rienzo C, Calvello M, Signore G, Di Matteo P, Gobbo F, Turturro S, Meucci S, Viegi A, Beltram F, Luin S and Cattaneo A (2016) Precursor and mature NGF live tracking: one versus many at a time in the axons.  Scientific Reports; 6:20272. doi: 10.1038/srep20272.

De Stasi AM, Farisello P, Marcon I, Cavallari S, Forli A, Vecchia D, Losi G, Mantegazza M, Panzeri S, Carmignoto G, Bacci A, Fellin T (2016). Unaltered Network Activity and Interneuronal Firing During Spontaneous Cortical Dynamics In Vivo in a Mouse Model of Severe Myoclonic Epilepsy of Infancy. Cereb Cortex 26:1778-1794

Di Primio C, Quercioli V, Siano G, Kovacech B, Novak B and Cattaneo A (2016) Conformational dynamics of Tau in the cell quantified by an intramolecular FRET sensor in physiological and pathological contexts. BioRxiv doi: http://dx.doi.org/10.1101/041756.

Feligioni M, Mango D, Piccinin S, Imbriani P, Iannuzzi F, Caruso A, De Angelis F, Blandini F, Mercuri NB, Pisani A, Nisticò R (2016). Subtle alterations of excitatory transmission are linked to presynaptic changes in the hippocampus of PINK1-deficient mice. Synapse 2016 Feb 5. doi:10.1002/syn.21894.

Graziani M, Nisticò R. (2016). Gender difference in prescription opioid abuse: A focus on oxycodone and hydrocodone. Pharmacol Res 108:31-38.

Griguoli M, Sgritta M, Cherubini E (2016), Presynaptic BK channels control transmitter release: physiological relevance and potential therapeutic implications. The Journal of Physiology 594:3489-500.

Guglielmi L, Nardella M, Musa C, Iannetti I, Arisi I, D’Onofrio M, Storti A, Valentini A, Cacci E, Biagioni S, Augusti-Tocco G, D’Agnano I, Felsani A (2016). Lamin A/C Is Required for ChAT-Dependent Neuroblastoma Differentiation. Mol Neurobiol 54:3729-3744.

Lupascu CA, Morabito A, Merenda E, Marinelli S, Marchetti C, Migliore R, Cherubini E and Migliore M (2016). A General Procedure to Study Subcellular Models of Transsynaptic Signaling at Inhibitory Synapses. Front Neuroinform 10:23. doi: 10.3389/fninf.2016.00023.

Malerba F, Paoletti F, Cattaneo A (2016). NGF and proNGF reciprocal interference in immunoassays: open questions, criticalities and ways forward. Frontiers in Molecular Neuroscience, 2016 Aug 3;9:63. doi: 10.3389/fnmol.2016.00063.

Mango D, Weisz F, Nisticò R (2016). Ginkgolic Acid Protects against Aβ-Induced Synaptic dysfunction in the Hippocampus.. Front Pharmacol  7:401. Published 2016 Oct 26. doi:10.3389/fphar.2016.00401 

Matic I, Cocco S, Ferraina C, Martin-Jimenez R, Florenzano F, Crosby J, Lupi R, Amadoro G, Russell C, Pignataro G, Annunziato L, Abramov AY, Campanella M (2016) Neuroprotective coordination of cell mitophagy by the F1Fo-ATPase Inhibitory Factor 1. Pharmacol Res 103:56-68.

Mori F, Nisticò R, Nicoletti CG, Zagaglia S, Mandolesi G, Piccinin S, Martino G, Finardi A, Rossini PM, Marfia GA, Furlan R, Centonze D. (2016). RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis. Mult Scler 22:1405-1412.

Pandolfini L, Luzi E, Bressan D, Ucciferri N, Bertacchi M, Brandi R, Rocchiccioli S, D’Onofrio M, Cremisi F (2016). RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells.  Genome Biol 17(1):94. Published 2016 May 6. doi:10.1186/s13059-016-0952-x 

Paoletti F, de Chiara C, Kelly G, Covaceuszach S, Malerba F, Yan R, Lamba D, Cattaneo A, Pastore A. (2016). Conformational rigidity within plasticity promotes differential target recognition of Nerve Growth Factor. Front in Mol Biosci 2016 Dec 26;3:83. doi: 10.3389/fmolb.2016.00083.

Paparone S, Severini C, Ciotti MT, D’Agata V, Calissano P, Cavallaro S (2016).  Transcriptional landscapes at the intersection of neuronal apoptosis and substance P-induced survival: exploring pathways and drug targets. Cell Death Discov 2016;2:16050. Published 2016 Aug 1. doi:10.1038/cddiscovery.2016.50.

Severini C, Petrella C, Calissano P (2016). Substance P and Alzheimer’s Disease: Emerging Novel Roles. Curr Alzheimer Res 13:964-972.

Triaca V, Calissano P (2016). Impairment of the nerve growth factor pathway driving amyloid accumulation in cholinergic neurons: the incipit of the Alzheimer’s disease story? Neural Regen Res 11:1553-1556. 

Triaca V, Sposato V, Bolasco G, Ciotti MT, Pelicci P, Bruni AC, Cupidi C, Maletta R, Feligioni M, Nisticò R, Canu N, Calissano P (2016). NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer’s disease. Aging Cell 15:661-672. 

Vignoli B, Battistini G, Melani R, Blum R, Santi S, Berardi N, Canossa M (2016). Peri-Synaptic Glia Recycles Brain-Derived Neurotrophic Factor for LTP Stabilization and Memory Retention. Neuron 92:873-887. 

 

2015

Arisi I, D’Onofrio M, Brandi R, Cattaneo A, Bertolazzi P, Cumbo F, Felici G and Guerra C (2015). Time Dynamics of Protein Complexes in the AD11 Transgenic Mouse Model for Alzheimer’s Disease. BMC Neurosci. 2015;16:28. Published Apr 29. doi:10.1186/s12868-015-0155-5 

Bertacchi M, Lupo G, Pandolfini L, Casarosa S, D’Onofrio M, Pedersen RA, Harris WA, Cremisi F (2015). Activin/Nodal Signaling Supports Retinal Progenitor Specification in a Narrow Time Window during Pluripotent Stem Cell Neuralization. Stem Cell Reports 5:532-545 

Bertacchi M, Pandolfini L, D’Onofrio M, Brandi R, Cremisi F (2015). The double inhibition of endogenously-produced BMP and Wnt factors synergistically triggers dorsal telencephalic differentiation of mouse ES cells. Dev Neurobiol 75:66-79. 

Bobba A., Amadoro G., La Piana G., Calissano P., Atlante A. (2015). Glycolytic enzyme upregulation and numbness of mitochondrial activity characterize the early phase of apoptosis in cerebellar granule cells. Apoptosis 20:10-28.

Bobba A., Amadoro G., La Piana G., Petragallo V.A., Calissano P., Atlante A. (2015). Glucose-6-phosphate tips the balance in modulating apoptosis in cerebellar granule cells. FEBS Lett 589:651-658.

Borreca A., Gironi K., Amadoro G., Ammassari-Teule M (2015). Opposite Dysregulation of Fragile-X Mental Retardation Protein and Heteronuclear Ribonucleoprotein C Protein Associates with Enhanced APP Translation in Alzheimer Disease. Mol Neurobiol 53:3227-3234.

Busceti CL, Pietro PD, Riozzi B, Traficante A, Biagioni F, Nisticò R, Fornai F, Battaglia G, Nicoletti F, Bruno V (2015). 5-HT(2C) serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice. Pharmacol Res 99:258-268.

Cherubini E, Miles R (2015). The CA3 region of the hippocampus: how is it? What is it for? How does it do it? Front Cell Neurosci 9:19. doi: 10.3389/fncel.2015.00019. 

Chiavacci E, D’Aurizio R, Guzzolino E, Russo F, Baumgart M, Groth M, Mariani L, D’Onofrio M, Arisi I, Pellegrini M, Cellerino A, Cremisi F, Pitto L (2015). microRNA 19° replacement partially rescues fin and cardiac defects in Zebrafish model of Holt Oram Syndrome. Sci Rep 2015;5:18240. Published 2015 Dec 14. doi:10.1038/srep18240 

Corsetti V, Florenzano F, Atlante A, Bobba A, Ciotti MT, Natale F, Della Valle F, Borreca A, Manca A, Meli G, Ferraina C, Feligioni M, D’Aguanno S, Bussani R, Ammassari-Teule M, Nicolin V, Calissano P, Amadoro G (2015). NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer’s disease. Hum Mol Genet 24:3058-3081.

Covaceuszach S, Konarev P,  Cassetta A, Paoletti F, Svergun D, Lamba D, Cattaneo A(2015)  The conundrum of the “high affinity” NGF binding sites formation unveiled? Biophysical J 108(3):687-97. doi:10.1016/j.bpj.2014.11.3485.

Cristino L, Luongo L, Squillace M, Paolone G, Mango D, Piccinin S, Zianni E, Imperatore R, Iannotta M, Longo F, Errico F, Vescovi AL, Morari M, Maione S, Gardoni F, Nisticò R, Usiello A. (2015). d-Aspartate oxidase influences glutamatergic system homeostasis in mammalian brain. Neurobiol Aging 36:1890-1902. 

Fazio F, Lionetto L, Curto M, Iacovelli L, Cavallari M, Zappulla C, Ulivieri M, Napoletano F, Capi M, Corigliano V, Scaccianoce S, Caruso A, Miele J, De Fusco A, Di Menna L, Comparelli A, De Carolis A, Gradini R, Nisticò R, De Blasi A, Girardi P, Bruno V, Battaglia G, Nicoletti F, Simmaco M. (2015). Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia. Sci Rep 2015;5:17799. Published 2015 Dec 8. doi:10.1038/srep17799 

Ghiglieri V, Napolitano F, Pelosi B, Schepisi C, Migliarini S, Di Maio A, Pendolino V, Mancini M, Sciamanna G, Vitucci D, Maddaloni G, Giampà C, Errico F, Nisticò R, Pasqualetti M, Picconi B, Usiello A (2015). Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion. Sci Rep 2015;5:10933. Published 2015 Jul 20. doi:10.1038/srep10933 

Graziani M, Nisticò R. (2015). Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy. Front Pharmacol 6:122. Published 2015 Jun 9. doi:10.3389/fphar.2015.00122 

Hampel H, Schneider LS, Giacobini E, Kivipelto M, Sindi S, Dubois B, Broich K, Nisticò R, Aisen PS, Lista S. (2015). Advances in the therapy of Alzheimer’s disease: targeting amyloid beta and tau and perspectives for the future. Expert Rev Neurother 15:83-105.

Maino B, D’Agata V, Severini C, Ciotti MT, Calissano P, Copani A, Chang YC, DeLisi C, Cavallaro S (2015). Igf1 and Pacap rescue cerebellar granule neurons from apoptosis via a common transcriptional program.  Cell Death Discov  1:15029-. doi:10.1038/cddiscovery.2015.29 

Malerba F, Paoletti F, Bruni Ercole B, Materazzi S, Nassini R, Coppi E, Patacchini R, Capsoni S, Lamba D, Cattaneo A (2015). Functional Characterization of human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a “painless” lead investigational candidate for therapeutic application. PLoS ONE 10(9): e0136425. doi:10. 1371/journal.pone.0136425.

Marchetti L, Luin S, Bonsignore F, de Nadai T, Beltram F, Cattaneo A.(2015) Ligand induced dynmics of neurotrophin receptors investigated by single-molecule imaging approaches. Int J Mol Sci.16(1):1949-79. doi: 10.3390/ijms16011949. 

Meroni PL, Valentini G, Ayala F, Cattaneo A, Valesini G. (2015) New strategies to address the pharmacodynamics and pharmacokinetics of tumor necrosis factor (TNF) inhibitors: a systematic analysis. Autoimmun Rev.14(9):812-29. doi: 10.1016/j.autrev.2015.05.001.  

Nasca C, Zellia D, Bigio B, Piccinin S, Scaccianoce S, Nisticò R, McEwen BS (2015). Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity. Proc Natl Acad Sci U S A 112:14960-14965.

Nisticò R, Florenzano F, Mango D, Ferraina C, Grilli M, Di Prisco S, Nobili A, Saccucci S, D’Amelio M, Morbin M, Marchi M, Mercuri NB, Davis RJ, Pittaluga A, Feligioni M (2015). Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release. Sci Rep 5:9035. Published 2015 Mar 12. doi:10.1038/srep09035 

Paoletti F, Malerba F, Ercole BB, Lamba D, Cattaneo A (2015). A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor. Biochim Biophys Acta 1854:187-197.

Pellegrino M, Mancini F, Lucà R, Coletti A, Giacchè N, Manni I, Arisi I, Florenzano F, Teveroni E, Buttarelli M, Fici L, Brandi R, Bruno T, Fanciulli M, D’Onofrio M, Piaggio G, Pellicciari R, Pontecorvi A, Marine JC, Macchiarulo A, Moretti F (2015). Targeting the MDM2/MDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy. Cancer Res 75:4560-4572.

Petrocchi-Passeri P, Cero C, Cutarelli A, Frank C, Severini C, Bartolomucci A, Possenti R (2015).The VGF-derived peptide TLQP-62 modulates insulin secretion and glucose homeostasis. J Mol Endocrinol  54:227-239.

Reichwald K, Petzold A, Koch P, Downie BR, Hartmann N, Pietsch S, Baumgart M, Chalopin D, Felder M, Bens M, Sahm A, Szafranski K, Taudien S, Groth M, Arisi I, Weise A, Bhatt SS, Sharma V, Kraus JM, Schmid F, Priebe S, Liehr T, Görlach M, Than ME, Hiller M, Kestler HA, Volff JN, Schartl M, Cellerino A, Englert C, Platzer M (2015). Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish. Cell 163:1527-1538. 

Sanguanini M and Cattaneo A (2015) A protein-aggregation dependent scaling-free synaptic facilitation rule for neural network simulations. BioRxiv,  doi:http://dx.doi.org/10.1101/031856

Schepisi C, Pignataro A, Doronzio SS, Piccinin S, Ferraina C, Di Prisco S, Feligioni M, Pittaluga A, Mercuri NB, Ammassari-Teule M, Nisticò R, Nencini P. (2015). Inhibition of hippocampal plasticity in rats performing contrafreeloading for water under repeated administrations of pramipexole. Psychopharmacology 233:727-737.

Severini C, Lattanzi R, Maftei D, Marconi V, Ciotti MT, Petrocchi Passeri P, Florenzano F, Del Duca E, Caioli S, Zona C, Balboni G, Salvadori S, Nisticò R, Negri L (2015). Bv8/prokineticin 2 is involved in Abeta-induced neurotoxicity. Sci Rep 5:15301. Published 2015 Oct 19. doi:10.1038/srep15301. 

Stöhr R, Kappel BA, Carnevale D, Cavalera M, Mavilio M, Arisi I, Fardella V, Cifelli G, Casagrande V, Rizza S, Cattaneo A, Mauriello A, Menghini R, Lembo G, Federici M. TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice. Mol Metab 4:741-752.

2014

Amadoro G, Corsetti V, Sancesario GM, Lubrano A, Melchiorri G, Bernardini S, Calissano P, Sancesario G. (2014). Cerebrospinal fluid levels of a 20-22 kDa NH2 fragment of human tau provide a novel neuronal injury biomarker in Alzheimer’s disease and other dementias. J Alzheimers Dis 42:211-226. 

Amadoro G, Corsetti V, Florenzano F, Atlante A, Ciotti MT, Mongiardi MP, Bussani R, Nicolin V, Nori SL, Campanella M, Calissano P (2014). AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons. Neurobiol Dis 62:489-507.

Amadoro G, Corsetti V, Florenzano F, Atlante A, Bobba A, Nicolin V,  Nori SL, Calissano P (2014). Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathway. Front Aging Neurosci  Feb 18;6:18. doi: 10.3389/fnagi.2014.00018. 

Antonelli R, Pizzarelli R, Pedroni A, Fritschy JM, Del Sal G, Cherubini E, Zacchi P (2014).
Pin1-dependent signaling negatively affects GABAergic transmission by modulating neuroligin2/gephyrin interaction. Nature Commun. Oct 9;5:5066. doi: 10.1038/ncomms6066. 

Arisi I, D’Onofrio M, Brandi R, Malerba F, Paoletti F, Storti AE, Florenzano F,Fasulo L and Cattaneo A (2014). proNGF/NGF mixtures behave as a new ligand in the NGF-regulated transcriptional response in PC12 cells. BMC Neurosci 15:48. Published 2014 Apr 8. doi:10.1186/1471-2202-15-48  

Bianchi D, De Michele P, Marchetti C, Tirozzi B, Cuomo S, Marie H, Migliore M. (2014). Effects of increasing CREB-dependent transcription on the storage and recall processes in a hippocampal CA1 microcircuit. Hippocampus 24:165-177.

Cellot G and Cherubini C (2014). GABAergic signaling as therapeutic target for Autism Spectrum Disorders.  Front Pediatrics, DOI: 10.3389/fped.2014.00070.

Cellot G and Cherubini E (2014). Reduced inhibitory gate in the barrel cortex of Neuroligin3 R451C knock-in mice, an animal model of Autism Spectrum Disorders. Physiol Reports Jul 16;2(7):e12077. doi: 10.14814/phy2.12077. 

Colas D, Manca A, Delcroix JD., and Mourrain P. (2014). Orexin A and orexin receptor 1 axonal traffic in dorsal roots at the CNS/PNS interface. Front Neurosci 8:20. Published 2014 Feb 11. doi:10.3389/fnins.2014.00020 

Costanzi M, Saraulli D, Cannas S, D’Alessandro F, Florenzano F, Rossi-Arnaud C, Cestari V (2014). Fear but not fright: re-evaluating traumatic experience attenuates anxiety-like behaviors after fear conditioning. Front Behav Neurosci 2014 Aug 25;8:279. doi: 10.3389/fnbeh.2014.00279. 

Covaceuszach S, Konarev PV,  Cassetta A, Paoletti P, Svergun S, Lamba D, Cattaneo A (2014).  The conundrum of the “high affinity” NGF binding sites formation unveiled? Biophys J 108:687-697. 

Curatolo P, Ben-Ari Y, Bozzi Y, Catania MV, D’Angelo E, Mapelli L, Oberman LM, Rosenmund C, Cherubini E (2014). Synapses as therapeutic targets for autism spectrum disorders: an international symposium held in pavia on july 4th, 2014. Front Cell Neurosci 2014 Sep 29;8:309. doi: 10.3389/fncel.2014.00309. 

De Bartolo P,  Florenzano F, Burello L, Gelfo F, Petrosini L (2014). Activity-dependent structural plasticity of Purkinje cell spines in cerebellar vermis and hemisphere. Brain Struct Funct  220:2895-2904. 

Deleuze C, Pazienti A, and Bacci A (2014). Autaptic self-inhibition of cortical GABAergic neurons: Synaptic narcissism or useful introspection?, Curr Opin Neurobiol 26:64–71.

Errico F, Nisticò R, Di Giorgio A, Squillace M, Vitucci D, Galbusera A, Piccinin S, Mango D, Fazio L, Middei S, Trizio S, Mercuri NB, Teule MA, Centonze D, Gozzi A, Blasi G, Bertolino A, Usiello A. (2014). Free D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals.  Transl Psychiatry Jul 29;4:e417. doi: 10.1038/tp.2014.59.PMID:  25072322   

Federici M, Latagliata EC, Ledonne A, Rizzo FR, Feligioni M, Sulzer D, Dunn M, Sames D, Gu H, Nisticò R, Puglisi-Allegra S, Mercuri NB. (2014) .Paradoxical abatement of striatal dopaminergic transmission by cocaine and methylphenidate. J Biol Chem 289:264-274.

Fezza F, Marrone MC, Avvisati R,  Di Tommaso M, Lanuti M, Rapino C, Mercuri NB, Maccarrone M and Marinelli S (2014). Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting. Mol Cell Neurosci 62:1-9. IF: 3.84

Gasperi V, Evangelista D, Chiurchiù V, Florenzano F, Savini I, Oddi S, Avigliano L, Catani MV, Maccarrone M (2014). 2-Arachidonoylglycerol modulates human endothelial cell/leukocyte interactions by controlling selectin expression through CB1 and CB2 receptors. Int J Biochem Cell Biol. 2014 Apr 7. pii: S1357-2725(14)00111-3. doi: 10.1016/j.biocel.2014.03.028. 

Harkany T, Zeilhofer H and Cattaneo A (2014) Neurotrophin and endocannabinoid interactions in the neurobiology of pain. Editorial of the Europ. J. Neuroscience Special Issue on Pain Neurobiology, Eur J Neurosci. 2014 Feb;39(3):331-3. doi: 10.1111/ejn.12483. Invited editor for the Special issue

Iacovelli L, Felicioni M, Nisticò R, Nicoletti F, De Blasi A  (2014). Selective regulation of recombinantly expressed mGlu7 metabotropic glutamate receptors by G protein-coupled receptor kinases and arrestins.  Neuropharmacol 77:303-312

Lourenço J, Pacioni S, Rebola N, van Woerden GM, Marinelli S, DiGregorio D and Bacci A (2014). Cell-autonomous potentiation of perisomatic inhibition alters the temporal coding of layer 5 pyramidal neurons. Plos Biol Jul 8;12(7):e1001903. doi: 10.1371/journal.pbio.1001903. IF:9.343

Luongo L, Guida F, Imperatore R, Napolitano F, Gatta L, Cristino L, Giordano C, Siniscalco D, Di Marzo V, Bellini G, Petrelli R, Cappellacci L, Usiello A, de Novellis V, Rossi F, Maione S (2014). The A1 adenosine receptor as a new player in microglia physiology. Glia 62:122-132.

Maftei D, Marconi V, Florenzano F, Giancotti LA, Castelli M, Moretti S, Borsani E, Rodella LF, Balboni G, Luongo L, Maione S, Sacerdote P, Negri L, Lattanzi R (2014). Controlling the activation of the Bv8/Prokineticin system reduces neuroinflammation and abolishes thermal and tactile hyperalgesia in neuropathic animals. Br J Pharmacol  171:4850-4865.

Mattarocci S, Abbruzzese C, Mileo AM, Carosi M, Visca P, Vico C, Federico A, Vizza E, Corrado G, Arisi I, Felsani A, Paggi MG (2014). Identification of pivotal cellular factors involved in HPV-induced dysplastic and neoplastic cervical pathologies. J Cell Physiol 29:463-470. 

Mango D., Barbato G., Piccirilli S., M.B. Panico, M. Feligioni, C. Schepisi, M. Graziani, V. Porrini, M. Benarese, A. Lanzillotta, M. Pizzi,f, S. Pieraccini, M. Sironi, F. Blandini, F. Nicoletti, N.B. Mercuri, B.P. Imbimbo, R. Nisticò (2014). Electrophysiological and metabolic effects of CHF5074 in the hippocampus: Protection against in vitro ischemia. Pharmacol Res 81: 83-90.

Marchetti L, De Nadai T, Bonsignore F, Calvello M, Signore G, Viegi A, Beltram F, Luin S, Cattaneo A (2014). Site-Specific Labeling of Neurotrophins and Their Receptors via Short and Versatile Peptide Tags. PLoS One Nov 26;9(11):e113708. doi: 0.1371/journal.pone.0113708.

Maya-Vetencourt JF, Carucci NM, Capsoni S, Cattaneo A (2014). Amyloid plaque-independent deficit of early postnatal visual cortical plasticity in the 5XFAD transgenic model of Alzheimer’s disease. J Alzheimers Dis 42:103-107. 

Meli G, Lecci A, Manca A, Krako N, Albertini V, Benussi L, Ghidoni R, Cattaneo A (2014). Conformational targeting of intracellular Aβ oligomers demonstrates their pathological oligomerization inside the endoplasmic reticulum. Nat Commun  May 27;5:3867. doi: 10.1038/ncomms4867.

Mori F, Nisticò R, Mandolesi G, Piccinin S, Mango D, Kusayanagi H, Berretta N, Bergami A, Gentile A, Musella A, Nicoletti CG, Nicoletti F, Buttari F, Mercuri NB, Martino G, Furlan R, Centonze D (2014). Interleukin-1beta Promotes Long-Term Potentiation in Patients with Multiple Sclerosis. Neuromolecular Med 16:38-51.

Mori F, Rossi S, Piccinin S, Motta C, Mango D, Kusayanagi H, Bergami A, Studer V, Nicoletti CG, Buttari F, Barbieri F, Mercuri NB, Martino G, Furlan R, Nisticò R, Centonze D (2014). Synaptic plasticity and PDGF signaling defects underlie clinical progression in multiple sclerosis. J Neurosci 33:19112-19119. 

Nisticò R., Ferraina C., Marconi V., Blandini F., Negri L., Egebjerg J. and Feligioni M (2014). Age-related changes of protein SUMOylation balance in the AbPP Tg2576 mouse model of Alzheimer’s disease. Front Pharmacol Apr 7;5:63. doi: 10.3389/fphar.2014.00063.

Nisticò R, Mori F, Feligioni M, Nicoletti F, Centonze D (2014). Synaptic plasticity in multiple sclerosis and in experimental autoimmune encephalomyelitis. Philos Trans R Soc Lond B Biol Sc 2013;369(1633):20130162. Published 2013 Dec 2. doi:10.1098/rstb.2013.0162 

Paoletti F, Malerba F; Bruni Ercole B, Lamba D, Cattaneo A (2014). A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor. Biophys. and Biochem. Acta (BBA) Proteins and Proteomics 1854:187-197. 

Pedroni A, Minh D, Mallamaci A, Cherubini E (2014). Electrophysiological characterization of granule cells in the dentate gyrus immediately after birth. Front Cell Neurosci 8:44. doi: 10.3389/fncel.2014.00044 

Pignatelli M, Piccinin S, Molinaro G, Di Menna L, Riozzi B, Cannella M, Motolese M, Vetere G, Catania MV, Battaglia G, Nicoletti F, Nisticò R, Bruno V (2014). Changes in mGlu5 receptor-dependent synaptic plasticity and coupling to homer proteins in the hippocampus of Ube3A hemizygous mice modeling Angelman Syndrome. J Neurosci  34:4558-4566. 

Révy D, Jaouen F, Salin P, Melon C, Chabbert D, Tafi E, Concetta L, Langa F, Amalric M, Kerkerian-Le Goff L, Marie H, Beurrier C (2014). Cellular and behavioral outcomes of dorsal striatonigral neuron ablation: new insights into striatal functions. Neuropsychopharmacol 39:2662-2672. 

Scardigli R, Capelli P, Vignone D, Brandi R, Ceci M, La Regina F, Piras E, Cintoli S, Berardi N, Capsoni S, Cattaneo A (2014). Neutralization of Nerve Growth Factor impairs proliferation and differentiation of adult neural progenitors in the subventricular zone. Stem Cells 32:2516-2528. 

Severini C, Passeri PP, Ciotti M, Florenzano F, Possenti R, Zona C, Di Matteo A, Guglielmotti A, Calissano P, Pachter J, Mercanti D (2014). Bindarit, inhibitor of CCL2 synthesis, protects neurons against amyloid-β-induced toxicity. J Alzheimers Dis 38:281-293. 

Tiribuzi R, Crispoltoni L, Porcellati S, Di Lullo M, Florenzano F, Pirro M, Bagaglia F, Kawarai T, Zampolini M, Orlacchio A, Orlacchio A (2014). miR128 up-regulation correlates with impaired amyloid β(1-42) degradation in monocytes from patients with sporadic Alzheimer’s disease. Neurobiol Aging 35:345-356. 

Tzanoulinou S, Brandi R, Arisi I, D’Onofrio M, Urfer SM, Sandi C, Constam D, Capsoni S (2014). Pathogen-Free Husbandry Conditions Alleviate Behavioral Deficits and Neurodegeneration in AD10 Anti-NGF Mice. J Alzheimers Dis 38:951-964. 

Zacchi P, Antonelli R, Cherubini E (2014). Gephyrin phosphorylation in the functional organization and plasticity of GABAergic synapses. Front Cell Neurosci 8:103. Published 2014 Apr 9. doi:10.3389/fncel.2014.00103.

Zuccaro E, Bergami M, Vignoli B, Bony G, Pierchala BA, Santi S, Cancedda L and Canossa M (2014). Polarized Expression of p75NTR Specifies Axons During Development and Adult Neurogenesis, Cell Rep  7:138-152

 

2013

Antonucci F, Morini R, Corradini I, Fossati G, Menna E, Pozzi D, Pacioni S, Verderio C, Bacci A, Matteoli M (2013) “Reduced SNAP-25 alters short term plasticity at developing glutamatergic synapses”. EMBO Rep. 2013 Jun 4. doi: 10.1038/embor.2013.75.

Bergami M, Vignoli B, Motori E, Pifferi S, Zuccaro E, Menini A and Canossa M (2013) TrkB signaling directs the incorporation of newly-generated periglomerular cells in the adult olfactory bulb. J. Neurosci. 2013 Jul 10;33(28):11464-78. doi: 10.1523/JNEUROSCI.4812-12.2013.

Blasi G, Napolitano F, Ursini G, Di Giorgio A, Caforio G, Taurisano P, Fazio L, Gelao B, Attrotto M T, Colagiorgio L, Todarello G, Piva F, Papazacharias A, Masellis R, Mancini M, Porcelli A, Romano R, Rampino A, Quarto T, Giulietti M, Lipska B K, Kleinman J E, Popolizio T, Weinberger D R, Usiello A, Bertolino A. GSK-3β genetic variation is associated with GSK-3β expression, prefrontal cortical thickness, prefrontal physiology, and schizophrenia. Am J Psychiatry.  2013 Aug 1;170(8):868-76. doi: 10.1176/appi.ajp.2012.12070908.

Bobba A, Amadoro G, Petragallo VA, Calissano P, Atlante A. (2013) Dissecting the molecular mechanism by which NH2htau and Aβ1-42 peptides impair mitochondrial ANT-1 in Alzheimer disease. Biochim Biophys Acta. 2013 Jul;1827(7):848-60. doi: 10.1016/j.bbabio.2013.04.001. Epub 2013 Apr 11.

Bonito-Oliva A, Pignatelli M, Spigolon G, Yoshitake T, Seiler S, Longo F, Piccinin S, Kehr J, Mercuri NB, Nisticò R, Fisone G (2013) Cognitive impairment and dentate gyrus synaptic dysfunction in experimental parkinsonism. Biol Psychiatry. 2013 Mar 28. doi:pii: S0006-3223(13)00183-2. 10.1016/j.biopsych.2013.02.015.

Campolongo P, Ratano P, Ciotti MT, Florenzano F, Nori SL, Marolda R, Palmery M, Rinaldi AM, Zona C, Possenti R, Calissano P, Severini C (2013) Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. PLoS One. 2013 Nov 12;8(11):e78036. doi: 10.1371/journal.pone.0078036.

Capsoni S, Carucci N,  Nykjaer A and Cattaneo A (2013) Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation. Biochem Biophys Res Commun. 431(3):579-85. doi: 10.1016/j.bbrc.2013.01.007. Epub 2013 Jan 11.

Cattaneo A (2013) Immunosympathectomy: the first protein silencing with antibodies. Proc. Natl. Acad. Sci. USA 110(13):4877-85. doi: 10.1073/pnas.1217586110.

Cavallucci V, Ferraina C, D’Amelio M (2013) Key role of mitochondria in synaptic transmission and plasticity. Curr Pharm Des. 2013 Feb 13.

Chao MV, Calissano P. (2013) Rita Levi-Montalcini: in memoriam. Neuron. 2013 Feb 6;77(3):385-7.

Cheung VK, Deboer C, Tunesi M, D’Onofrio M, Brandi R, Arisi I, Cattaneo A, Goosens KA, Gene Expression Changes in the Motor Cortex Mediating Motor Skill Learning (2013) PLoS One. 2013 Apr 24;8(4):e61496.

Chlystun M, Campanella M, Law AL, Duchen MR, Fatimathas L, Levine TP, Gerke V, Moss SE. (2013) Regulation of mitochondrial morphogenesis by annexin A6. PLoS One. 2013;8(1):e53774. doi: 10.1371/journal.pone.0053774. Epub 2013 Jan 14.

Faccenda D, Tan CH, Seraphim A, Duchen MR, Campanella M. (2013) IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ. 2013 May; 20(5):686-97. doi: 10.1038/cdd.2012.163. Epub 2013 Jan 25.

Feligioni M, Mattson MP, Nisticò R. (2013) SUMOylation in neuroplasticity and neurological disorders.  Neuromolecular Med. 2013 Dec;15(4):637-8. No abstract available.  PMID:  24354012  

Feligioni M, Nisticò R. (2013) SUMO: a (oxidative) stressed protein. Neuromolecular Med. 2013 Dec;15(4):707-19. doi: 10.1007/s12017-013-8266-6. Epub 2013 Sep 20. Review. PMID:  24052421  

Ferri A, Favaro R, Beccari L, Bertolini J, Mercurio S, Nieto-Lopez F, Verzeroli C, La Regina F, De Pietri Tonelli D, Ottolenghi S, Bovolenta P, Nicolis SK. (2013) Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh. Development.140(6):1250-61. 

Fiorentino L, Cavalera M, Menini S, Mavilio M, Fabrizi M, Conserva F, Casagrande V, Menghini R, Arisi I, D’Onofrio M, Lauro D, Accili D, Gesualdo L, Pugliese G, Lauro R, Federici M (2013) Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay, EMBO Mol Med; 5(3):441-55. doi: 10.1002/emmm.201201475. Epub 2013 Feb 12

Griguoli M, Cellot G, Cherubini E (2013). In hippocampal oriens interneurons anti-Hebbian Long-Term Potentiation requires cholinergic signalling via ɑ7 nicotinic acetylcholine receptors. Journal of Neuroscience, 33(3):1044-1049.

Keimpema E, Tortoriello G, Alpár A, Capsoni S, Arisi I, Calvigioni D, Hu SS, Cattaneo A, Doherty P, Mackie K, Harkany T. (2013) Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1935-40. doi: 10.1073/pnas.1212563110. Epub 2013 Jan 14

Krako N, Magnifico MC, Arese M, Meli G, Forte E, Lecci A, Manca A, Giuffrè A, Mastronicola D, Sarti P, Cattaneo A. (2013) Characterization of mitochondrial dysfunction in the 7PA2 cell model of Alzheimer’s disease. J Alzheimers Dis. 37(4):747-58. doi: 10.3233/JAD-130728

La Rosa LR, Matrone C, Ferraina C, Panico MB, Piccirilli S, Di Certo MG, Strimpakos G, Mercuri NB, Calissano P, D’Amelio M, Nisticò R. (2013) Age-related changes of hippocampal synaptic plasticity in AβPP-null mice are restored by NGF through p75NTR. J Alzheimers Dis. 2013 Jan 1;33(1):265-72.

Marchetti L, Callegari A, Luin S, Signore G, Viegi A, Beltram F, Cattaneo A. (2013) Ligand signature in the membrane dynamics of single TrkA receptor molecules. J Cell Sci.126(Pt 19):4445-56. doi: 10.1242/jcs.129916. Epub 2013 Jul 25.

Meli G, Krako N, Manca A, Lecci A, Cattaneo A. (2013) Intrabodies for protein interference in Alzheimer’s disease. Journal of Biological Regulators & Homeostatic Agents. Vol 27, Number 2, SUPPL., 89-105  

Niklison-Chirou MV, Steinert JR, Agostini M, Knight RA, Dinsdale D, Cattaneo A, Mak TW, Melino G (2013)  TAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptor. Proc Natl Acad Sci U S A. 110(47):18952-7. doi: 10.1073/pnas.1221172110. Epub 2013 Nov 4.

Nisticò R, Mango D, Mandolesi G, Piccinin S, Berretta N, Pignatelli M, Feligioni M, Musella A, Gentile A, Mori F, Bernardi G, Nicoletti F, Mercuri NB, Centonze D. Inflammation subverts hippocampal synaptic plasticity in experimental multiple sclerosis. Plos One. 8(1):e54666.

Nisticò R, Piccinin S, Schepisi C, Ferraina C, Laurenza M, Mango D, Graziani M, Nicoletti F, Mercuri NB, Feligioni M. (2013) Pharmacological modulation of long-term potentiation in animal models of Alzheimer’s disease. J Biol Regul Homeost Agents. 2013 Apr-Jun;27(2 Suppl):37-47. PMID:   24813314 

Noguera N, Song MS, Calvo KL, Divona MD, Catalano G, Faraoni I, Ottone T, Florenzano F, Battistini L, Colombo E, García F, Amadori S, Pandolfi PP, Lo-Coco F. (2013) Interation of nucleophosmin with deubiquinilating protease HAUSP induces PTEN nuclear depletion in acute myeloid leukemia. Leukemia. 2013 Apr; 27(5):1037-43. doi: 10.1038/leu.2012.314.

Nori SL, Rocco ML, Florenzano F, Ciotti MT, Aloe L and Manni L. (2013) Increased nerve growth factor signaling in sensory neurons of early diabetic rats is corrected by electroacupuncture. 

Evid Based Complement Alternat Med. 2013;2013:652735. doi: 10.1155/2013/652735. Epub 2013 Apr 21.

Novakovic D, Feligioni M, Scaccianoce S, Caruso A, Piccinin S, Schepisi C, Errico F, Mercuri NB, Nicoletti F, Nisticò R. (2013) Profile of gantenerumab and its potential in the treatment of Alzheimer’s disease. Drug Des Devel Ther. 2013 Nov 13;7:1359-64. doi: 10.2147/DDDT.S53401. eCollection 2013. Review. Erratum in: Drug Des Devel Ther. 2014;8:569. PMID: 24255592

Parisi C.,Arisi I., D’Ambrosi N., Brandi R., Storti A., D’Onofrio M., Volonté (2013) “Dysregulated microRNAs in Amyotrophic Lateral Sclerosis microglia modulate genes linked to neuroinflammation”, Cell Death Dis. 2013 Dec 12;4:e959. doi: 10.1038/cddis.2013.491. 

Park DM, Jung J, Masjkur J, Makrogkikas S, Ebermann D, Saha S, Rogliano R, Paolillo N, Pacioni S, McKay RD, Poser S, Androutsellis-Theotokis A. (2013) Hes3 regulates cell number in cultures from glioblastoma multiforme with stem cell characteristics. Sci Rep; 3:1095. doi: 10.1038/srep01095. Epub 2013 Feb 5.

Pazienti A and Bacci A, (2013) Role of cell type and synaptic connections during functionally relevant network states in vitro, BMC Neuroscience 2013, 14(Suppl 1):P311.

Pignatelli M, Vollmayr B, Richter SH, Middei S, Matrisciano F, Molinaro G, Nasca C, Battaglia G, Ammassari-Teule M, Nisticò R, Nicoletti F, Gass P. (2013) Enhanced mGlu5 receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats. Neuropharmacology. 66:339-47.

Pignatelli M, Feligioni M, Piccinin S, Molinaro G, Nicoletti F, Nisticò R. (2013) Synaptic plasticity as a therapeutic target in the treatment of autism-related single-gene disorders. Curr Pharm Des. 2013 Feb 13.

Repele A, Lupi R, Eaton S, Urbani L, De Coppi P, Campanella M. (2013) Cell metabolism sets the differences between subpopulations of satellite cells (SCs). BMC Cell Biol. 2013 May 3;14(1):24.

Romani A, Marchetti C, Bianchi D, Leinekugel X, Poirazi P, Migliore M, Marie H. (2013) Computational modeling of the effects of amyloid-beta on release probability at hippocampal synapses. Frontiers in Computational Neuroscience, 7:1. DOI: 10.3389/fncom.2013.00001

Schena F, Volpi S, Faliti CE, Penco F, Santi S, Proietti M, Schenk U, Damonte G, Salis A, Bellotti M, Fais F, Tenca C,  Gattorno M, Eibel H, Rizzi M, Warnatz K, Idzko M, Ayata K, Rakhmanov M, Galli T, Martini A, Canossa M, Grassi F, Traggiai E (2013) Dependence of immunoglobulin class switch recombination in B cells on vesicular release of ATP and CD73 ectonucleotidase activity. Cell Report 2013 Jun 27;3(6):1824-31. doi: 10.1016/j.celrep.2013.05.022. Epub 2013 Jun 13.

Tirassa P, Maccarone M, Florenzano F, Cartolano S, De Nicolò S. (2013) Vascular and neuronal protection induced by the ocular administration of nerve growth factor in diabetic-induced rat encephalopathy. CNS Neurosci Ther. 2013 May; 19(5):307-18. doi: 10.1111/cns.12085.

Tiveron C, Fasulo L, Capsoni S, Malerba F, Marinelli S, Paoletti F, Piccinin S, Scardigli R, Amato G, Brandi R, Capelli P, D’Aguanno S, Florenzano F, La Regina F, Lecci A, Manca A, Meli G, Pistillo L, Berretta N, Nisticò R, Pavone F, Cattaneo A. (2013) ProNGF/NGF imbalance triggers neurodegeneration and spontaneous epileptic-like discharges in transgenic mice. Cell Death Differ. 2013 Mar 29. doi: 10.1038/cdd.2013.22.

Vara DS, Campanella M, Canobbio I, Dunn WB, Pizzorno G, Hirano M, Pula G. (2013) Autocrine amplification of integrin αIIbβ3 activation and platelet adhesive responses by deoxyribose-1-phosphate. Thromb Haemost. 2013 Mar 14;109(5).

Schena F, Volpi S, Faliti CE, Penco F, Santi S, Proietti M, Schenk U, Damonte G, Salis A, Bellotti M, Fais F, Tenca C,  Gattorno M, Eibel H, Rizzi M, Warnatz K, Idzko M, Ayata K, Rakhmanov M, Galli T, Martini A, Canossa M, Grassi F, Traggiai E (2013) Dependence of immunoglobulin class switch recombination in B cells on vesicular release of ATP and CD73 ectonucleotidase activity. Cell Report 2013 Jun 27;3(6):1824-31. doi: 10.1016/j.celrep.2013.05.022. Epub 2013 Jun 13.

 

2012 

Amadoro G, Corsetti V, Atlante A, Florenzano F, Capsoni S, Bussani R, Mercanti D, Calissano P. Interaction between NH2-tau fragment and Abeta in AD mitochondria contributes to the synaptic deterioration. Neurobiology of Aging, 2012 April; 33(4):833.e1-25.

Barbato C, Ruberti F, (2012) The role of microRNA regulation of neuronal differentiation and plasticity, In: Mallick B (eds) Regulatory RNAs: Springer-Verlag Berlin Heidelberg (2012)

Bianchi D, Marasco A, Limongiello A, Marchetti C, Marie H, Tirozzi B, Migliore M. (2012)”On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons” Journal of Computational Neuroscience, 33(2):207-25.

Bornstein SR, Ehrhart-Bornstein M, Androutsellis-Theotokis A, Eisenhofer G, Licinio J, Wong M.L, Calissano P, Nisticò G, Levi-Montalcini R, (2012) Chromaffin Cells – The Peripheral Brain, Molecular Psychiatry17(4):354-8.

Calissano P, Amadoro G (2012) NGF at the interface between physiology and pathology of AβPP processing. European Journal of Neurodegenerative Diseases, 1(1): 35-52.

Callegari A, Luin S, Marchetti L, Duci A, Cattaneo A, Beltram F (2012). Single particle tracking of acyl carrier protein (ACP)-tagged TrkA receptors in PC12nnr5 cells. J Neurosci Methods 204, 82-86.

Campanella M. (2012) The Physiology and Pharmacology of the mitochondrial 18-kd translocator protein (TSPO): an emerging molecular target for diagnosis and therapy, Current Molecular Medicine, 12(4):355.

Campanella M. (2012) Impaired Mitochondrial Metabolism in Neurodegeneration, European Journal of Neurodegenerative Diseases, 1(2): 185-198.

Capsoni S, Carlo AS, Vignone D, Amato G, Criscuolo C, Willnow TE, Cattaneo A (2012) SorLA Deficiency Dissects Amyloid Pathology from Tau and Cholinergic Neurodegeneration in a Mouse Model of Alzheimer’s Disease. J Alzheimers Dis. 33(2):357-71. doi: 10.3233/JAD-2012-121399.

Capsoni S., Carucci N.M., Cattaneo A. (2012) Pathogen free conditions slow the onset of  neurodegeneration in a mouse model of Nerve Growth Factor  deprivation. J. Alzheimers Dis 31(1):1-6

Capsoni S, Marinelli S, Ceci M, Vignone D, Amato G, Malerba F, Paoletti F, Meli G, Viegi A, Pavone F, Cattaneo A. Intranasal “painless” human Nerve Growth Factors slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice. PLoS One. 2012;7(5):e37555

Cattaneo A, Calissano P. (2012) Nerve growth factor and Alzheimer’s disease: new facts for an old hypothesis. Mol Neurobiol. 2012 Dec;46(3):588-604. doi: 10.1007/s12035-012-8310-9. Epub 2012 Sep 1.

Cattaneo A, Meli G (2012) Protein silencing with intrabodies: targeting Alzheimer’s disease proteins, European Journal of Neurodegenerative Diseases, 1(2): 149-166.

Ceci M, Welshhans K, Ciotti MT, Brandi R, Parisi C, Paoletti F, Pistillo L, Bassell GJ and Cattaneo A (2012) RACK1 is a ribosome scaffold protein for β -actin mRNA/ ZBP1complex. PLoS One, 7(4):e35034.

Cherubini A, Nisticò G, Rozzini R, Liperoti R, Di Bari M, Zampi E, Ferrannini Aguglia E, Pani L, Bernabei R, Marchionni N, Trabucchi M (2012) Subtreshold depression in older subjects: an unmet therapeutic need. J. Nutr., Health and Aging, 16(10):909-13.

Covaceuszach S., Marinelli S., Krastanova I., Ugolini G., Pavone F., Lamba D., Cattaneo A. (2012) Single Cycle Structure-based Humanization of an Anti-Nerve Growth Factor Therapeutic Antibody, PLoS One, 7(3):e32212

Esposito S, Pristerà A, Maresca G, Cavallaro S, Felsani A, Florenzano F, Manni L, Ciotti MT, Borsello T Canu N. Involvment of Serine racemase/D-serine pathway in cerebellar granule neurons apoptosis. Cell Aging, 2012 Apr 16. doi: 10.1111/j.1474-9726.2012.00822.x.

Errico F, Napolitano F, Nisticò R, Usiello A. (2012) New insights on the role of free D-aspartate in the mammalian brain. Amino Acids. 2012 Nov;43(5):1861-71.

Errico F, Napolitano F, Vitucci D, Di Maio A, Squillace M, Marsili V, Marmo F, Chiariotti L, Usiello A. Role of D-aspartate in glutamatergic neurotransmission: new insights from animal models. Eur J Neurodeg Dis. 1(3):267-278.

Falco A, Festa M, Basile A, Rosati A, Pascale M, Florenzano F, Nori SL, Nicolin V, Di Benedetto M, Vecchione ML, Arra C, Barbieri A, De Laurenzi V, Turco MC. BAG3 controls angiogenesis through regulation of ERK phosphorylation. Oncogene, 13;31(50):5153-61.

Florenzano F. Localization of axonal motor molecules machinery in neurodegenerative disorders. Int J Mol Sci. 2012;13(4):5195-206.

Gatliff J. and Campanella M. (2012) The 18Kda translocator Protein (TSPO): a new perspective in mitochondrial biology, Current Molecular Medicine, 12(4):356-68.

Grasselli G, Rossi S, Musella A, Gentile A, Loizzo S, Muzio L, Di Sanza C, Errico F, Musumeci G, Haji N, Fresegna D, Sepman H, De Chiara V, Furlan R, Martino G, Usiello A, Mandolesi G, Centonze D. (2012) Abnormal NMDA receptor function exacerbates experimental autoimmune encephalomyelitis. Br J Pharmacol. 168(2):502-17.

Griguoli M, Cherubini E (2012). Regulation of hippocampal inhibitory circuits by nicotinic acetylcholine receptors. Journal of Physiology, 590 (4):655-666. Review article.

Grilli M, Summa M, Salamone A, Olivero G, Zappettini S, Di Prisco S, Feligioni M, Usai C, Pittaluga A, Marchi M. (2012) In vitro exposure to nicotine induces endocytosis of presynaptic AMPA receptors modulating dopamine release in rat nucleus accumbens nerve terminals. Neuropharmacology; 63(5):916-26.

Latella L, Palacios D, Forcales S, Puri PL (2012) Epigenetic control of reprogramming and cellular differentiation. Comp Funct Genomics; 2012:538639. Epub 2012 Sep 17.

Klionsky DJ et al (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8(4):445-544.

Kittappa R, Bornstein SR, Androutsellis-Theotokis A (2012) The role of endogenous stem cells in neurodegenerative disease. Molecular Neurobiology, 46(3):555-62.

Manca A, Capsoni S, Di Luzio A, Vignone D, Malerba F, Paoletti F, Brandi R, Arisi I, Cattaneo A, and Levi-Montalcini R (2012) Nerve growth factor regulates axial rotation during early stages of chick embryo development, Proc Nat Acad Sci, 109(6):2009-14

Maresca G, Natoli M, Nardella M, Arisi I, Trisciuoglio D, Desideri M, Brandi R, D’Aguanno S, Nicotra MR, D’Onofrio M, Urbani A, Natali PG, Bufalo DD, Felsani A, D’Agnano I. LMNA Knock-Down Affects Differentiation and Progression of Human Neuroblastoma Cells. PLoS One. 2012;7(9):e45513.

Maya-Vetencourt JF, Baroncelli L, Viegi A, Tiraboschi E, Castren E, Cattaneo A and Maffei L (2012) IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels. Neural Plasticity, 2012:250421.

Nisticò R., Collingridge G. (2012) The synaptic basisof Alzheimer’s disease. European Journal of Neurodegenerative Diseases, 1(1):21-33.

Nisticò R, Pignatelli M, Piccinin S, Mercuri NB, Collingridge G (2012) Targeting synaptic disfunction in Alzheimer’s disease therapy. Mol. Neurobiol., 46(3):572-87.

Nisticò R, Cavallucci V, Piccinin S, Macrì S, Pignatelli M, Mehdawy B, Laviola G, Mercuri NB, D’Amelio M (2012) Insulin receptor haploinsufficiency impairs long-term plasticity in the hippocampus. Neuromolecular Med, 14(4):262-9.

Pacioni S, Rueger, MA, Nistico, G, McKay, RD, Bornstein, SR, and Androutsellis-Theotokis, A, Fast, potent pharmacological expansion of putative endogenous neural stem cell / progenitor cell populations in the adult mouse and rat hippocampus, PLoS ONE, 7(12):e51630. doi: 10.1371/journal.pone.0051630.

Paoletti F, Malerba F, Konarev P.V., Visintin M, Scardigli R, Fasulo L, Lamba D, Svergun DI, Cattaneo A (2012) Direct intracellular selection and biochemical characterization of a recombinant anti-proNGF single chain antibody fragment. Arch Biochem Biophys.; 522(1):26-36

Rossi S, Sacchetti L, Napolitano F, De Chiara V, Motta C, Studer V, Musella A, Barbieri F, Bari M, Bernardi G, Maccarrone M, Usiello A, Centonze D. (2012) Interleukin-1β Causes Anxiety by Interacting with the Endocannabinoid System. J Neurosci; 32(40):13896.

Severinatne M, Faccenda D, De Biase V and Campanella M (2012) Mitochondrial degradation is limited by PK11195: functional implications for the F1Fo-ATPsynthase in Mitophagy, Current Molecular Medicine, 12(4):476-82.

Scarpi D, Cirelli D, Matrone C, Castronovo G, Rosini P, Occhiato EG, Romano F, Bartali L, Clemente AM, Bottegoni G, Cavalli A, De Chiara G, Bonini P, Calissano P, Palamara AT, Garaci E, Torcia MG, Guarna A, Cozzolino F (2012) Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity. Cell Death Dis. 2012 Sep 6;3:e389. doi: 10.1038/cddis.2012.129.

Su T, Scardigli R, Fasulo L, Paradiso B, Barbieri M, Binaschi A, Bovolenta R, Zucchini S, Cossu G, Cattaneo A, Simonato M. Bystander effect on brain tissue of mesoangioblasts producing neurotrophins. Cell Transplant; 21(8):1613-27.