From Synapses to Neurodegeneration

Lunedì 12 Luglio 2010 - Martedì 13 Luglio 2010

Conference in honor of Rita Levi-Montalcini

hosted by Consiglio Nazionale delle Ricerche (CNR)

Aula Marconi, Piazzale Aldo Moro, Rome, Italy
Free Attendance-No Registration

Organising Secretariat:
Pina Moliterno, Pamela Bernardo, Krupesh Mistry

Email: scientific.assist@ebri.it

Program Schedule

Monday 12th July

9:00-9:15 WELCOME ADDRESS
Gianluigi Condorelli, Giuseppe Martini, Giuseppe Nisticò, Gerry Melino

9:15-10:15 KEYNOTE LECTURE
Chair: Giuseppe Nisticò
Sir Salvador Moncada (United Kingdom)
“Neurons, mitochondria, astrocytes, glycolysis... what is the connection with cancer?”


Session 1 CELL BIOLOGY OF NEURONS
Chairs: Richard A. Knight, Lilia Alberghina


10:15-10:45 Gerry Melino (Italy)
“p73 is involved in synaptogenesis via miR-34a”

10:45-11:15 Paolo Salomoni (United Kingdom)
“Role of the tumour suppressor PML in adult neural stem cells”

11:15-11:45 COFFEE BREAK – THE ARANGIO RUIZ HALL

11:45-12:15 Antonio Simeone (Italy)
“Otx2 in adult meso-diencephalic dopaminergic neurons”

12:15-13:15 KEYNOTE LECTURE in memory of J.D. Delcroix*
Chair: Ian Forsythe

Pierluigi Nicotera (Germany)
“Synaptic dysfunction in neurodegeneration”

13:15-15:00 LUNCH – THE ARANGIO RUIZ HALL


Session 2 SYNAPTIC TRANSMISSION AND NEURONAL CIRCUITS
Chairs: Nicolas Bazan


15:00-15:30 Ian Forsythe (United Kingdom)
“The calyx of Held as a modelfor neurodegeneration and activity-dependent plasticity”

15:30-16:00 Alberto Bacci (Italy)
“Self-inhibiting neurons in the neocortex”

16:00-16:30 Enrico Cherubini (Italy)
“Early network activity in the developing hippocampus”

16:30-17:00 COFFEE BREAK –THE ARANGIO RUIZ HALL

17:00-17:15 Daniele Bano (Germany) – short presentation
“Potential new genes involved in ageing and neurodegeneration”

17:15-18:15 KEYNOTE LECTURE
Chair: Pierluigi Nicotera

Nicolas Bazan (USA)
“Downregulation or amyloidogenic processing of amyloid-β-precursor protein via PPARγ and of pro-inflammatory effect by neuroprotectin D1”


Tuesday 13th July

9:00-10:00 KEYNOTE LECTURE
Chair: Alberto Bacci

Adriano Aguzzi (Switzerland)
“Prion Disease”


Session 3 NEURODEGENERATION
Chairs: Gerry Melino, Giorgio Bernardi


10:00-10:30 Alexei Verkhratsky (United Kingdom)
“Neuroglial roots of neurodegeneration”

10:30-11:00 Frédéric Checler (France)
“Neurodegeneration in Alzheimer´s and Parkinson´s diseases: p53 as a common denominator?”

11:00-11:30 COFFEE BREAK –THE ARANGIO RUIZ HALL

11:30-12:00 L. Miguel Martins (United Kingdom)
“Mitochondrial Quality Control and Parkinson´s Disease”

12:00-12:30 Simona Capsoni (Italy)
“Linking Nerve Growth Factor to Alzheimer’s disease”

12:30-13:00 Hélène Marie (Italy)
“Chronic NGF deprivation, Alzheimer’s disease and hippocampal plasticity”

13:00-13:30 Pietro Calissano (Italy)
“A tight link between NGF receptors and APP metabolism”

13:30-13:40 CONCLUDING REMARKS
Nicolas Bazan, Giuseppe Nisticò, Gerry Melino

* Lecture is in memory of Jean Dominique Delcroix, Group Leader at EBRI, responsible for the Neurodegenerative and Axon Dynamics Laboratory. Dr. Delcroix passed away on June 22, 2007 at the age of 39.